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| | 2-(3,4-Dichlorophenyl)-4-fluoroaniline Basic information |
| Product Name: | 2-(3,4-Dichlorophenyl)-4-fluoroaniline | | Synonyms: | 3',4'-dichloro-5-fluoro-[1,1'-biphenyl]-2-aMine;[1,1']-biphenyl-2-aMine-3',4'-dichloro-5-fluoro;2-(3,4-Dichlorophenyl)-4-fluoroaniline;3',4'-Dichloro-5-fluorobiphenyl-2-amine;2-amino-5-fluoro-3,4-dichlorobenzene;2- amino -5- fluoro -3',4'- dichlorobiphenyl;3',4'-Dichloro-5-fluoro-[1,1'-biphenyl]-2-amine;2- amino -5- fluoro -3',4'- dichlorobiphenyl | | CAS: | 877179-04-9 | | MF: | C12H8Cl2FN | | MW: | 256.1 | | EINECS: | 700-287-9 | | Product Categories: | | | Mol File: | 877179-04-9.mol |  |
| | 2-(3,4-Dichlorophenyl)-4-fluoroaniline Chemical Properties |
| Boiling point | 357℃ at 101.3kPa | | density | 1.47 at 20℃ | | storage temp. | 2-8°C | | pka | 3.22±0.10(Predicted) | | LogP | 4.3 at 22℃ and pH7 |
| | 2-(3,4-Dichlorophenyl)-4-fluoroaniline Usage And Synthesis |
| Synthesis | 8.15 g (97%, 0.042 mol) of 3,4-dichlorophenylboronic acid are initially charged in 50 g of water and 50 g toluene. Subsequently, 18.7 g (0.085 mol) of potassium phosphate and 8.2 g (98%, 0.042 mol) of 2-bromo-4-fluoroaniline are added. After blanketing with nitrogen, 0.014 g (0.00002 mol) of 1,1'-bis(di-test-butyl phosphine) ferrocene palladium dichloride is added, and the mixture is stirred for two hours at 79-81° C. The organic phase is separated and evaporated under reduced pressure, leaving 10.5 g of an oil-crystallized 2-(3,4-Dichlorophenyl)-4-fluoroaniline.
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| | 2-(3,4-Dichlorophenyl)-4-fluoroaniline Preparation Products And Raw materials |
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