N4-苯甲酰基-5'-O-DMT-2'-氟-脱氧胞苷-3'-氰乙氧基亚磷酰胺
中文名称 | N4-苯甲酰基-5'-O-DMT-2'-氟-脱氧胞苷-3'-氰乙氧基亚磷酰胺 |
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中文同义词 | N-苯甲酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脱氧-2'-氟胞苷 3'-[2-氰基乙基 N,N-二异丙基氨基亚磷酸酯];2-F-RC(N-BZ) 亚磷酰胺单体;N-苯甲酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脱氧-2'-氟胞苷 3'-[2-氰基乙基 N,N-二异丙基氨基亚磷酸酯;N4-苯甲酰基-5'-O-DMT-2'-氟-脱氧胞苷-3'-氰乙氧基亚磷酰胺;(2R,3R,4R,5R)-5-(4-BENZAMIDO-2-OXOPYRIMIDIN-1(2H)-YL)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-FLUOROTETRAHYDROFURAN-3-YL (2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE;(2R,3R,4R,5R)-5-(4-苯甲酰胺基-2-氧代嘧啶-1(2H)-基)-2-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-4-氟四氢呋喃 -3-基(2-氰乙基)二异丙基亚磷酰胺;2'-F-DC(BZ) 亚磷酰胺单体;2'-F-BZ-DC-CE-亚磷酰胺 |
英文名称 | N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite |
英文同义词 | N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite;N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite;Bz-2'-F-dC Phosphoramidite;N4-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine-3'-CE-Phosphoramidite;Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];2''-Fluoro-n4-benzoyl-5''-o-dmt-2''-deoxycytidine-3''-ce-phosphoramidite;2'-fluoro-N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-CE-Phosphoramidite |
CAS号 | 161442-19-9 |
分子式 | C46H51FN5O8P |
分子量 | 851.9 |
EINECS号 | |
相关类别 | 核苷;有机化工;亚磷酰胺单体 |
Mol文件 | 161442-19-9.mol |
结构式 |
N4-苯甲酰基-5'-O-DMT-2'-氟-脱氧胞苷-3'-氰乙氧基亚磷酰胺 性质
储存条件 | Store at -20°C |
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溶解度 | DMSO:100 mg/mL(117.38 mM;需要超声波) |
酸度系数(pKa) | 8.50±0.20(Predicted) |
形态 | 固体 |
颜色 | 白色至浅黄色 |
N4-苯甲酰基-5'-O-DMT-2'-氟-脱氧胞苷-3'-氰乙氧基亚磷酰胺是一种荧光寡核苷酸RNA探针,也用于提高代谢稳定性和诱导有效的RNAi介导的基因沉默。