2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE manufacturers
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| 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Basic information |
Product Name: | 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE | Synonyms: | VAN BOOM'S REAGENT;2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE;ChloroHbenzodioxaphosphorinone;2-Chloro-4H-1,2,3-benzodioxaphosphorin-4-one 90%;2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE 97%;NSC 40209;Salicylchlorophosphite
Van Boom's Reagent;2-Chloro-4H-1,3,2-benzodioxaphosphinin-4-one | CAS: | 5381-99-7 | MF: | C7H4ClO3P | MW: | 202.53 | EINECS: | | Product Categories: | Phospholipids - 13C & 2H;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Phosphorylating and Phosphorothioating Agents;Phosphorylation;Protecting Agents, Phosphorylating Agents & Condensing Agents;Synthetic Organic Chemistry;Phosphorylating and Phosphitylating Agents | Mol File: | 5381-99-7.mol | ![2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Structure](CAS/GIF/5381-99-7.gif) |
| 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Chemical Properties |
Melting point | 36-40 °C (lit.) | Boiling point | 127-128 °C/11 mmHg (lit.) | Fp | >230 °F | storage temp. | 2-8°C | solubility | Soluble in acetonitrile, dichloromethane, tetrahydrofuron and dimethylformamide. | form | solid | color | White or Colorless to Orange to Green | BRN | 1311951 | Stability: | Water Sensitive | CAS DataBase Reference | 5381-99-7(CAS DataBase Reference) |
Hazard Codes | C | Risk Statements | 14-34-37 | Safety Statements | 26-36/37/39-43-45 | RIDADR | UN 3261 8/PG 1 | WGK Germany | 3 | F | 3-10 | Hazard Note | Corrosive | HazardClass | 8 | PackingGroup | II | HS Code | 29349990 |
| 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Usage And Synthesis |
Chemical Properties | White Crystalline Solid | Uses | 2-Chloro-1,3,2-benzodioxaphosphorin-4-one is used as a reagent:
- In the phosphorylation and phosphitylation of alcohols.
- In the formation of H-phosphonates which are commonly utilized in the synthesis of nucleotides.
- To synthesize nucleoside triphosphates by treating with acyl protected nucleoside.
| Uses | Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs | Uses | 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one is a reagent used in phosphorylation and phosphitylation of alcohols and in the formation of H-phosphonates. It is also reactive cyclic phosphitylating reagent involved in fast coupling rates and hydrolytic cleavage more readily compare to that of a acyclic analog. |
| 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Preparation Products And Raw materials |
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