丝拉克肽
中文名称 | 丝拉克肽 |
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中文同义词 | 丝拉克肽;六氟硅酸;促肾上腺皮质激素(1-39);丝拉克肽, ≥97% (HPLC);人ACTH (1-39)肽;SERACTIDE、丝拉克肽;促肾上腺皮质激素ACTH(1-39);促肾上腺皮质激素ACTH(1-39), HUMAN丝拉克肽 |
英文名称 | Seractide |
英文同义词 | CORTICOTROPIN (HUMAN);CORTICOTROPHIN;CORTICOTROPIN A;H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH;ACTH (1-39) (huMan) Corticotropin;Adrenocorticotropic Hormone (ACTH) (1-39);Seractide acetate;ACTH (1-39), HUMAN |
CAS号 | 12279-41-3 |
分子式 | C207H308N56O58S1 |
分子量 | 4541.07 |
EINECS号 | 634-154-0 |
相关类别 | 多肽中间体;细胞生物学;细胞信号和神经生物学;多肽系列;原料药;多肽;生化试剂-蛋白质;药物多肽;Peptide;Melanocortin receptor |
Mol文件 | 12279-41-3.mol |
结构式 |
丝拉克肽 性质
储存条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
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溶解度 | H2O:1 mg/mL,澄清,无色 |
形态 | 固体 |
颜色 | 白色至米白色 |
水溶解性 | Soluble to 1 mg/ml in water |
序列 | H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH |
Melanocortin receptor
Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH 1-39), a member of the melanocortin family, stimulates production of CS by the adrenals, but melanocortin receptors are also found in the central nervous system (CNS) and on immune cells. ACTH 1-39 protects neurons in vitro from several apoptotic, excitotoxic and inflammation-related insults. The conditioned medium (CM) is prepared from untreated astroglia (AS) cultures and from AS cultures treated with 200 nM ACTH 1-39 for 24 h, washed to remove ACTH 1-39, then incubated for another 24 h in DMEM. In initial experiments, no difference is found in oligodendroglia (OL) viability in the presence of OL definedmediumwith 2% newborn calf serum (NCS) or AS CM (prepared in DMEM with no serum). After 24 h, OL death under each condition varies between 1 and 4%. Similar results for OL viability are obtained with microglia (MG) CM. In subsequent experiments, controls in each experiment consist of OL in defined medium with 2% NCS.
醋酸根含量5.0%~12.0%
水分含量≤8.0%
肽含量≥80.0%
安全信息
危险品标志 | Xn |
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危险类别码 | 20/21/22-40 |
安全说明 | 22-36 |
WGK Germany | 3 |
RTECS号 | GM7900000 |
F | 8-10 |
提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-P1211 | 丝拉克肽 Adrenocorticotropic Hormone (ACTH) (1-39), human | 12279-41-3 | 1mg | 2200元 |
2024/08/19 | HY-P1211 | 丝拉克肽 Adrenocorticotropic Hormone (ACTH) (1-39), human | 12279-41-3 | 5mg | 4500元 |