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Sigma-Aldrich
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| Products Intro: |
Product Name:MST-312
CAS:368449-04-1
Purity:>=98% (HPLC) Package:25MG Remarks:M3949-25MG
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MST-312 manufacturers
- MST-312
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- $44.00 / 5mg
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2024-11-19
- CAS:368449-04-1
- Min. Order:
- Purity: 99.17%
- Supply Ability: 10g
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| | MST-312 Basic information |
| Product Name: | MST-312 | | Synonyms: | TELOMERASE INHIBITOR IX;MST-312;N,N'-BIS(2,3-DIHYDROXYBENZOYL)-1,3-PHENYLENEDIAMINE;N,N′-1,3-Phenylenebis-[2,3-dihydroxy-benzamide];Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem;N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide;Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-;MST-312 >=98% (HPLC) | | CAS: | 368449-04-1 | | MF: | C20H16N2O6 | | MW: | 380.35 | | EINECS: | | | Product Categories: | | | Mol File: | 368449-04-1.mol |  |
| | MST-312 Chemical Properties |
| Boiling point | 526.7±50.0 °C(Predicted) | | density | 1.578±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: ≥20mg/mL | | form | White solid | | pka | 7.70±0.35(Predicted) | | color | off-white to light tan |
| Hazard Codes | N | | Risk Statements | 50 | | Safety Statements | 61 | | WGK Germany | 2 |
| | MST-312 Usage And Synthesis |
| Uses | MST-312 has been used in cell invasion assay using mouse fibroblast cells (NIH-3T3) and in the co-immunoprecipitation experiments in colon fibroblast. | | Definition | ChEBI: N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide is a member of benzamides. | | General Description | A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 μM). | | Biochem/physiol Actions | Cell permeable: yes |
| | MST-312 Preparation Products And Raw materials |
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