N-OMEGA-PROPYL-L-ARGININE
中文名称 | N-OMEGA-PROPYL-L-ARGININE |
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中文同义词 | |
英文名称 | N-OMEGA-PROPYL-L-ARGININE |
英文同义词 | L-N5-(1-IMINO-9-PROPYLAMINO-O-METHYL)ORINTHINE;L-N5-(1-IMINO(PROPYLAMINO))METHYL-ORNITHINE;2(S)-2-AMINO-5-(N-PROPYLGUANIDINO)PENTANOIC ACID;N5-[IMINO(PROPYLAMINO)METHYL]-L-ORNITHINE;NW-PROPYL-L-ARGININE;N-PLA;N-OMEGA-PROPYL-L-ARGININE;NG-PROPYL-L-ARGININE |
CAS号 | 137361-05-8 |
分子式 | C9H20N4O2 |
分子量 | 216.28 |
EINECS号 | |
相关类别 | All Inhibitors;Inhibitors;Nitric Oxide Reagents;Amino Acids & Derivatives |
Mol文件 | 137361-05-8.mol |
结构式 | ![]() |
N-OMEGA-PROPYL-L-ARGININE 性质
熔点 | 198-200?C |
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沸点 | 366.5±52.0 °C(Predicted) |
密度 | 1.24±0.1 g/cm3(Predicted) |
储存条件 | Desiccate at RT |
溶解度 | 可溶于氯仿(少许)、甲醇(少许) |
酸度系数(pKa) | 2.50±0.24(Predicted) |
形态 | 白色至类白色固体。 |
颜色 | 白色 |
稳定性 | 非常吸湿 |
CAS 数据库 | 137361-05-8(CAS DataBase Reference) |
Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) 是一种高效、竞争性、高选择性的神经型一氧化氮合酶 (nNOS) 抑制剂,Ki为 57 nM。Nω-Propyl-L-arginine 对 nNOS 的选择性是内皮型一氧化氮合酶 (eNOS) 的 149 倍。
Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) (20 mg/kg; i.p.) blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity.
Animal Model: | Male NMRI mice (30-40 g) (phencyclidine-induced stimulation) |
Dosage: | 20 mg/kg |
Administration: | I.p. |
Result: | Markedly reduced the phencyclidineinduced disruption of prepulse inhibition and significantly reduced the phencyclidine-induced stimulation of locomotor activity. |
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-102062A | N-OMEGA-PROPYL-L-ARGININE Nω-Propyl-L-arginine hydrochloride | 137361-05-8 | 5mg | 940元 |
2024/08/19 | HY-102062A | N-OMEGA-PROPYL-L-ARGININE Nω-Propyl-L-arginine hydrochloride | 137361-05-8 | 10mg | 1500元 |