6-氮杂胸腺嘧啶
中文名称 | 6-氮杂胸腺嘧啶 |
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中文同义词 | 6-氮杂胸腺嘧啶;6-吖胸嘧啶;6-氮胸嘧啶;氮杂胸腺嘧啶;氮杂胸腺嘧啶,6;1,2,4-三嗪-3,5(2H,4H)-二酮,6-甲基-;3,5-二羟基-6-甲基-1,2,4-三嗪;5-甲基-6-氮尿嘧啶 |
英文名称 | 6-AZATHYMINE |
英文同义词 | 1,2,4-TRIAZINE-3,5(2H,4H)-DIONE, 6-METHYL-;6-AZA-5-METHYLURACIL;6-AZA-2,4-DIHYDROXY-5-METHYL-PYRIMIDINE;6-AZATHYMINE;6-METHYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE;3,5-DIHYDROXY-6-METHYL-1,2,4-TRIAZINE;6-Azathymine,98%;6-METHYL-S-TRIAZINE-3,5-DIONE |
CAS号 | 932-53-6 |
分子式 | C4H5N3O2 |
分子量 | 127.1 |
EINECS号 | 213-253-9 |
相关类别 | 酰胺;酰胺化合物;Vitamins and Derivatives;Nucleic acids |
Mol文件 | 932-53-6.mol |
结构式 | ![]() |
6-氮杂胸腺嘧啶 性质
熔点 | 210-212°C |
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沸点 | 235.85°C (rough estimate) |
密度 | 1.4748 (rough estimate) |
折射率 | 1.5000 (estimate) |
酸度系数(pKa) | 7.6(at 25℃) |
形态 | 粉末晶体 |
颜色 | 白色到近乎白色 |
Merck | 14,903 |
BRN | 126863 |
InChIKey | XZWMZFQOHTWGQE-UHFFFAOYSA-N |
CAS 数据库 | 932-53-6(CAS DataBase Reference) |
6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine.
The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5- 14 C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives.
安全信息
安全说明 | 22-24/25 |
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RTECS号 | XY8050000 |
海关编码 | 2934.10.9000 |
危险等级 | IRRITANT |