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Tripeptide-1

Tripeptide-1 Suppliers list
Company Name: GIHI CHEMICALS CO.,LIMITED
Tel: +8618058761490
Email: info@gihichemicals.com
Products Intro: Product Name:gly-his-lys acetate
CAS:72957-37-0
Purity:99 Package:5KG;1KG,25kg
Company Name: Strong peptide cross-border e-commerce Co. LTD
Tel: +undefined13930052870
Email: qt01@qiangtaipharm.com
Products Intro: Product Name:Tripeptide-1
CAS:72957-37-0
Purity:99+ Package:1box;80.00;USD|5box;78.00;USD|10box;75.00;USD
Company Name: Hubei Chuyunshun Biotechnology Co., Ltd.
Tel: +86-15926415536 +86-15926415536
Email: hbcyssw@163.com
Products Intro: Product Name:Tripeptide-1
CAS:72957-37-0
Purity:0.99 Package:5KG;1KG
Company Name: Changsha MOL Changes Biotechnology Co., Ltd.
Tel: +8619375158599
Email: info@molchanges.com
Products Intro: Product Name:Tripeptide-1
CAS:72957-37-0
Purity:99% Package:5mg;10mg;100mg;1g;10g;100g
Company Name: Shanghai Yunao International Trade Co., Ltd
Tel: +8617621705551
Email: asdf@shanghaihg.cn
Products Intro: Product Name:Liver Cell Growth Factor acetate salt
CAS:72957-37-0
Purity:99% Package:1g;50USD

Tripeptide-1 manufacturers

  • Tripeptide-1
  • Tripeptide-1 pictures
  • $0.00 / 1kg
  • 2025-02-02
  • CAS:72957-37-0
  • Min. Order: 0.10000000149011612kg
  • Purity: ≥99%
  • Supply Ability: 20tons
  • Tripeptide-1
  • Tripeptide-1 pictures
  • $1.00 / 1kg
  • 2025-01-24
  • CAS:72957-37-0
  • Min. Order: 0.0001kg
  • Purity: 99%
  • Supply Ability: 50kg
  • GHK-HAC
  • GHK-HAC pictures
  • $0.00/ kg
  • 2025-01-21
  • CAS:72957-37-0
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1T+
Tripeptide-1 Basic information
Product Name:Tripeptide-1
Synonyms:H-GLY-HIS-LYS-OH ACETATE SALT;H-GLY-HIS-LYS-OH ACOH;GLY-HIS-LYS ACETATE;GLY-HIS-LYS ACETATE SALT;GLY-HIS-LYS ACOH H2O;GLYCYL-L-HISTIDYL-L-LYSINE ACETATE;LIVER CELL GROWTH FACTOR;LIVER CELL GROWTH FACTOR ACETATE SALT
CAS:72957-37-0
MF:C16H28N6O6
MW:400.44
EINECS:277-125-4
Product Categories:Amino Acid Derivatives;72957-37-0
Mol File:72957-37-0.mol
Tripeptide-1 Structure
Tripeptide-1 Chemical Properties
storage temp. -20°C
form powder
color white
biological sourcesynthetic (organic)
Water Solubility H2O: soluble 0.5mg/mL, clear, colorless
SequenceGly-His-Lys
InChIKeyMGNUTAFMLGJBGV-ACMTZBLWSA-N
SMILESC(=O)(O)C.[C@@H](NC(=O)CN)(C(=O)N[C@H](C(=O)O)CCCCN)CC1N=CNC=1 |&1:4,13,r|
CAS DataBase Reference72957-37-0(CAS DataBase Reference)
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
Tripeptide-1 Usage And Synthesis
DescriptionTripeptide-1 is a small peptide composed of three amino acids  (glycine-histidine-lysine or GHK) and is known for type I collagen fragments. When collagen fragment peptides (GHK) are added, it may mistakenly lead the skin to think that collagen has been broken down, resulting in more collagen. Therefore, tripeptide-1 is believed to stimulate collagen production in the skin. More collagen will reduce wrinkles on the face, which will improve the condition of the skin.
Chemical PropertiesWhite powder
UsesLiver Cell Growth Factor
UsesGly-His-Lys acetate salt has been used:
  • individually or as a complex with copper to test its effect on cytokines production in the human normal fibroblasts cell lines
  • as a model peptide in N,N-dimethyl-N-methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine based capillary electrophoresis separation studies
  • as a component of Coon′s modified Ham′s F-12 medium for culturing Fischer rat thyroid follicular cell line, FRTL-5

General DescriptionGly-His-Lys is a tripeptide present at ~200ng/ml in association with α-globulin and albumin, in human blood plasma.
Biochem/physiol ActionsGly-His-Lys (GHK) acetate salt displays affinity towards copper(II) ions. This property enables GHK to modulate the copper intake into cells. GHK is also involved in quenching toxic by-products generated by lipid peroxidation.
in vitroIn an enzyme assay, the liver growth factor, Tripeptide-1, was hydrolyzed by an aminotripeptidase purified from rat brain cytosol[1].
in vivoTripeptide-1 (1% in saline; dose = 10 mg/kg) was injected into the tail vein of male rats (number not specified). Blood samples were collected prior to dosing and for up to 60 minutes post-dosing. Plasma concentration-time profiles of Tripeptide-1 and its l-histidyl-l-lysine metabolite indicated that neither was detected in predose plasma samples. However, after intravenous (IV) injection, Tripeptide-1 was rapidly degraded to l histidyl-l-lysine, rapidly eliminated from circulating blood. It has been reported that Tripeptide-1 is unstable in human plasma and is rapidly degraded by aminopeptidases[1].
References[1] Wilbur Johnson. “Safety Assessment of Tripeptide-1, Hexapeptide-12, Their Metal Salts and Fatty Acyl Derivatives, and Palmitoyl Tetrapeptide-7 as Used in Cosmetics.” International Journal of Toxicology 37 1 (2018): 102S–90S.
Tripeptide-1 Preparation Products And Raw materials
Tag:Tripeptide-1(72957-37-0) Related Product Information
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