Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:Methacetin-13C CAS:72156-70-8 Package:50Mg,5Mg
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| METHACETIN-METHOXY-13C Basic information |
| METHACETIN-METHOXY-13C Chemical Properties |
Melting point | 128-130 °C(lit.) | storage temp. | Refrigerator | solubility | Acetone, Alcohol, Chloroform (Sparingly), Methanol (Slightly) | form | Powder | color | Crystalline | Stability: | Light and moisture sensitive |
Hazard Codes | Xn | Risk Statements | 22 | WGK Germany | 3 | RTECS | AE8290000 | HS Code | 28459000 |
| METHACETIN-METHOXY-13C Usage And Synthesis |
Chemical Properties | METHACETIN-METHOXY-13C is Crystalline Powder | Uses | METHACETIN-METHOXY-13C is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis. | Uses | Labelled Methacetin (M258772) is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis. | Definition | ChEBI: Methacetin-(methoxy-(13)C) is a (13)C-modified compound that is methacetin which has (13)C as the predominant isotope of the methoxy carbon. In normal subjects, methacetin is rapidly metabolised in the liver, being dealkylated by hepatic CYP1A2 to give paracetamol (acetaminophen); the methyl of the methoxy group is eliminated as CO2. Administering methacetin-(methoxy-(13)C) to a patient enables the liver (cytochrome P-450 1A2) function to be determined quickly and precisely by measuring the (13)CO2 in the breath (e.g. by isotope-selective non-dispersive infrared spectrometry (NDIRS)). It has a role as an isotopic tracer and a diagnostic agent. It is a (13)C-modified compound, a member of acetamides and an aromatic ether. |
| METHACETIN-METHOXY-13C Preparation Products And Raw materials |
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