DPO-1 manufacturers
- DPO-1
-
- $1.00 / 1KG
-
2024-08-24
- CAS:43077-30-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100000KG
|
| Product Name: | DPO-1 | | Synonyms: | DPO-1;[1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide;(+)-Neomenthyl diphenylphosphine oxide;(1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide;Phosphine oxide, [(1S,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl-;DOP-1 (Diphenyl phosphine oxide-1);inhibit,DPO1,Inhibitor,DPO 1,Potassium Channel,DPO-1,KcsA;{[(1S,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl](phenyl)phosphoroso}benzene | | CAS: | 43077-30-1 | | MF: | C22H29OP | | MW: | 340.44 | | EINECS: | | | Product Categories: | | | Mol File: | 43077-30-1.mol |  |
| | DPO-1 Chemical Properties |
| storage temp. | Store at +4°C | | solubility | DMSO: soluble2mg/mL, clear (warmed) | | form | needles | | color | white |
| | DPO-1 Usage And Synthesis |
| Definition | ChEBI: [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene is a monoterpenoid. | | Biological Activity | Blocker of I Kur ultrarapid delayed rectifier potassium current and K V 1.5 channels (IC 50 = 0.31 μ M for rK V 1.5). Displays selectivity for inhibition of I Kur over I to (8-fold), I K1 , I Kr and I Ks (20-fold) in native myocytes and selectivity for rat recombinant K V 1.5 over K V 3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia. | | storage | Store at +4°C |
| | DPO-1 Preparation Products And Raw materials |
|