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| liriodenine Basic information |
Product Name: | liriodenine | Synonyms: | liriodenine;8H-Benzo[G]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one;Micheline b;Noraporphin-7-one, 4,5,6,6A-tetradehydro-1,2-(methylenedioxy)-;Nsc93681;Oxoushinsunin;Oxoushinsunine;Spermatheridin | CAS: | 475-75-2 | MF: | C17H9NO3 | MW: | 275.26 | EINECS: | | Product Categories: | | Mol File: | 475-75-2.mol | |
| liriodenine Chemical Properties |
Melting point | 282°C | Boiling point | 531.0±19.0 °C(Predicted) | density | 1.501±0.06 g/cm3(Predicted) | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | form | powder | pka | 2.67±0.20(Predicted) | color | Yellow |
| liriodenine Usage And Synthesis |
Description | Isolated from the heartwood extract of Liriodendron tulip/era, this base may be
purified by crystallization from CHCI3. It contains one methylenedioxy group
and a keto group, forming a crystalline oxime, m.p. 271°C. The structure has
been confirmed by synthesis, the synthetic alkaloid having a higher melting
point of 287°C. | Uses | Liriodenine is an isoquinoline alkaloid found in extracts of medicinal Asian vegetation such as Michelia alba and Liriodendron chinense. | Definition | ChEBI: An oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities. | target | p53 | Caspase | Bcl-2/Bax | Sodium Channel | Potassium Channel | Topoisomerase | cAMP | References | Buchanan, Dickey.,J. Org. Chern., 25, 1389 (1960)
Taylor., Tetrahedron, 14,42 (1961) |
| liriodenine Preparation Products And Raw materials |
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