2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- manufacturers
- CCR2-RA-[R]
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- $39.00 / 2mg
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2024-11-19
- CAS:512177-83-2
- Min. Order:
- Purity: 99.70%
- Supply Ability: 10g
- CCR2-RA-[R]
-
- $39.00 / 2mg
-
2024-11-19
- CAS:512177-83-2
- Min. Order:
- Purity: 99.70%
- Supply Ability: 10g
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| 2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Basic information |
Product Name: | 2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- | Synonyms: | 2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-;(R)-4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one;187305;(R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1H-pyrrol-2(5H)-one;(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one;CCR,Inhibitor,inhibit,CCR-2-RA-[R],CC chemokine receptor,CCR2RA[R],CCR2 RA [R;4-ACETYL-1-(4-CHLORO-2-FLUOROPHENYL)-5-CYCLOHEXYL-3-HYDROXY-5H-PYRROL-2-ONE | CAS: | 512177-83-2 | MF: | C18H19ClFNO3 | MW: | 351.8 | EINECS: | | Product Categories: | | Mol File: | 512177-83-2.mol | |
| 2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Chemical Properties |
Boiling point | 482.6±45.0 °C(Predicted) | density | 1.383±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 1 mg/ml | form | A crystalline solid | pka | 4.50±1.00(Predicted) | color | White to off-white |
| 2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Usage And Synthesis |
Uses | (5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one, is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM. |
| 2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Preparation Products And Raw materials |
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