GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL
| 中文名称 | GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL |
|---|---|
| 中文同义词 | MELAN-A, MART 1 (26-35),EAAGIGILTV;MART-1蛋白片段多肽MART-1 (26-35) (HUMAN) |
| 英文名称 | H-GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL-OH |
| 英文同义词 | H-GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL-OH;GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL;EAAGIGILTV;ANTIGEN SK29-AA (26-35) (HUMAN);ANTIGEN LB39-AA (26-35) (HUMAN);MART 1 (26-35);MART-1 (26-35) (HUMAN);MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 (26-35) (HUMAN) |
| CAS号 | 156251-01-3 |
| 分子式 | C42H74N10O14 |
| 分子量 | 943.1 |
| EINECS号 | |
| 相关类别 | 多肽;标准品;peptide |
| Mol文件 | 156251-01-3.mol |
| 结构式 |  |
GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL 性质
| 沸点 | 1358.4±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.223±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C |
| 酸度系数(pKa) | 3.32±0.10(Predicted) |
MART-1 (26-35) (human) 是 MART-1 蛋白 26 至 35 氨基酸片段。
MART-1 (Melan-A) gene is 18 kb long and comprises five exons. It is expressed in most melanoma tumor samples, and among normal cells, only in melanocytes. In cancer immunotherapy, epitopes and variants derived from the MART-1/Melan-A protein are widely used as clinical vaccines. The epitopes spanning amino acid residues 26–35 and 27–35 from the MART-1/Melan-A protein, highly expressed in melanoma cells, provide a prime example of T cell recognition of multiple peptides and the use of peptide variants designed to elicit altered immunological responses.