- Rubusoside
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- $45.00 / 1kg
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2025-04-25
- CAS:64849-39-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20 tons
- RUBUSOSIDE
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- $10.00 / 1kg
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2025-04-23
- CAS:64849-39-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100 mt
- RUBUSOSIDE
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- $0.00 / 1KG
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2025-04-15
- CAS:64849-39-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
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| | RUBUSOSIDE Basic information |
| | RUBUSOSIDE Chemical Properties |
| Melting point | 178～181℃ | | Boiling point | 802.5±65.0 °C(Predicted) | | density | 1.45 | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly) | | form | Solid | | pka | 12.51±0.70(Predicted) | | color | White to Off-White | | optical activity | [α]/D -37 to -47°, c =0.5 in methanol | | Stability: | Hygroscopic | | InChIKey | YWPVROCHNBYFTP-OSHKXICASA-N |
| WGK Germany | 3 | | HS Code | 29389090 |
| | RUBUSOSIDE Usage And Synthesis |
| Uses | Rubusoside is used as a nutritive sweetener, derived from .Stevia rebaudiana Stevia glycosiede. | | Definition | ChEBI: Rubusoside is a steviol glycoside that is steviol in which both the carboxy group and the tertiary allylic hydroxy group have been converted to their corresponding beta-D-glucosides. A precious bioactive natural sweetener which mainly exists the in Chinese sweet tea plant, Rubus suavissimus. It has a role as a sweetening agent and a plant metabolite. It is a beta-D-glucoside, a tetracyclic diterpenoid, a bridged compound and a steviol glycoside. It is functionally related to a steviol. | | Biological Activity | Rubusoside is a natural next generation sugar substitute isolated from Rubus suavissimus S. Lee. Rubusoside exhibits antiangiogenic and antiallergic properties. It can be used as a solubilizing agent for assorted biologically active agents. | | in vivo | Rubusoside (50-300 mg/kg; po; single dose) exerts anti-inflammatory and antiasthmatic activities in an OVA-induced experimental allergic asthma mouse model. Moreover, Rubusoside inhibits OVA-induced activation of the NF-κB pathway in lung tissue[4].
| Animal Model: | Ovalbumin‐induced mice allergic asthma model[4] | | Dosage: | 50, 150, 300 mg/kg | | Administration: | po; mixed with PBS (phosphate-buffered saline, pH 7.4) 1 hr before OVA treatment (intraperitoneal injected with 20 μg OVA and intranasal spray 1% OVA solution from Day 21 to Day 23) | | Result: | Contributed to the decrease of inflammatory cytokines (TNF-α, IL-13, IL-6, IL-5, and IL-4) inside the BALF of mice with asthma.
Led a decline of OVA-dependent IgE and IgG1 inside the serum was also noticed in these mice.
Enhanced the mRNA level of Foxp3 inside the mice lung affected with asthma while decrease that of IL-17A, IL-23, and RORγt.
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| | RUBUSOSIDE Preparation Products And Raw materials |
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