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| 4-Biphenylcarbonyl chloride Basic information |
| 4-Biphenylcarbonyl chloride Chemical Properties |
Melting point | 110-112 °C (lit.) | Boiling point | 160 °C / 2mmHg | density | 1.1459 (rough estimate) | refractive index | 1.5260 (estimate) | storage temp. | Inert atmosphere,Room Temperature | form | Fine Crystalline Powder | color | White to yellow | Water Solubility | HYDROLYSIS | Sensitive | Moisture Sensitive/Lachrymatory | BRN | 472842 | InChIKey | JPVUWCPKMYXOKW-UHFFFAOYSA-N | CAS DataBase Reference | 14002-51-8(CAS DataBase Reference) | EPA Substance Registry System | [1,1'-Biphenyl]-4-carbonyl chloride (14002-51-8) |
Hazard Codes | C | Risk Statements | 14-34 | Safety Statements | 26-36/37/39-43-45-25 | RIDADR | UN 3261 8/PG 2 | WGK Germany | 3 | F | 21-10 | Hazard Note | Corrosive/Lachrymatory/Moisture Sensitive | TSCA | Yes | HazardClass | 8 | PackingGroup | II | HS Code | 29163990 |
| 4-Biphenylcarbonyl chloride Usage And Synthesis |
Chemical Properties | 4-Biphenylcarbonyl chloride is white to yellow fine crystalline powder | Uses | Biphenyl-4-carbonyl chloride was used in the preparation of a novel thiourea compound, N-(6-methyl pyridin-2-yl-carbamothioyl)biphenyl-4-carboxamide. It was also used in the preparation of 5-CF3-oxazole analog, 2-{4-[2-(2-biphenyl-4-yl-5-trifluoromethyl-oxazol-4-yl)-ethoxy]-phenoxy}-2-methyl-propionic acid. | Purification Methods | Dissolve the carbonyl chloride in a large volume of pet ether (10 x, b 50-70o), filter it through a short column of neutral alumina, evaporate to dryness in vacuo and recrystallise it from pet ether (b 60-80o). [Beilstein 9 IV 2480.] LACHRYMATORY. |
| 4-Biphenylcarbonyl chloride Preparation Products And Raw materials |
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