抗痛素
| 中文名称 | 抗痛素 |
|---|---|
| 中文同义词 | 抗蛋白酶;抗痛素;抗蛋白酶, 2盐酸;化合物 T14295 |
| 英文名称 | ANTIPAIN HYDROCHLORIDE DIHYDRATE |
| 英文同义词 | N2-[[(1-Carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide;PHE-ARG-VAL-ARG-CHO;Antipain research grade;4-((aminoiminomethyl)amino)-1-formylbutyl)-;ANTIPAIN HYDROCHLORIDE DIHYDRATE;N2-[[(1-carboxyphenethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide;ANTIPAIN ~10000 U/MG;Nα-[N2-[[(1-Carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl]-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide |
| CAS号 | 37691-11-5 |
| 分子式 | C27H44N10O6 |
| 分子量 | 604.7 |
| EINECS号 | 253-631-0 |
| 相关类别 | A - K;Aldehydes;Antibacterial;Antibiotics A to Z;Antibiotics;Antibiotics A-F;Antibiotics by Application;Antineoplastic and Immunosuppressive Antibiotics;Building Blocks;C13-C60;Carbonyl Compounds;Chemical Structure Class;Chemical Synthesis;Inhibits an Enzyme;Mechanism of Action;Organic Building Blocks;Peptides;Spectrum of Activity;Pepetides |
| Mol文件 | 37691-11-5.mol |
| 结构式 |  |
抗痛素 性质
| 密度 | 1.38 |
|---|---|
| 储存条件 | −20°C |
| 酸度系数(pKa) | 3.84±0.10(Predicted) |
| BRN | 6837629 |
Antipain 是一种从 Actinomycetes 分离的蛋白酶 (protease) 抑制剂。Antipain 抑制 N-甲基-N'-硝基-N-亚硝基胍 (MNNG) 诱导的转化，增加染色体畸变。Antipain 限制小鼠中子宫 DNA 合成和功能。
The intact, cycling female mice received subcutaneous injections of Antipain (3 mg) for 16 days, their uteri shows significant diminution in weight and total DNA when compared to untreated controls.
Antipain (100 μg/g body wt; i.p.; at 12h intervals from 0 to 120 h or 240 to 360 h) shows inhibitory effect on Urethane-induced lung neoplasia in mice.
安全信息
| WGK Germany | 3 |
|---|---|
| RTECS号 | YV9350700 |
| F | 1-10 |