XLR11 N-(4-hydroxypentyl) metabolite (CRM)

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Products Intro: Product Name:XLR11 N-(4-hydroxypentyl) metabolite
CAS:1782099-36-8
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Products Intro: Product Name:4-Hydroxypentyl XLR11
CAS:1782099-36-8
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Products Intro: Product Name:4-Hydroxypentyl XLR11
CAS:1782099-36-8
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Products Intro: Product Name:XLR11 N-(4-hydroxypentyl) metabolite (CRM)
CAS:1782099-36-8
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Products Intro: Product Name:XLR-11 4-hydroxypentyl metabolite
CAS:1782099-36-8
Purity:1000 μg/mL in methanol
XLR11 N-(4-hydroxypentyl) metabolite (CRM) Basic information
Product Name:XLR11 N-(4-hydroxypentyl) metabolite (CRM)
Synonyms:XLR11 N-(4-hydroxypentyl) metabolite (CRM);[1-(5-fluoro-4-hydroxypentyl)indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone;XLR11 N-(4-hydroxypentyl) metabolite RM;4-Hydroxypentyl XLR11;XLR-11 4-hydroxypentyl metabolite;XLR11 N-(4-hydroxypentyl) metabolite;Methanone, [1-(5-fluoro-4-hydroxypentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-
CAS:1782099-36-8
MF:C21H28FNO2
MW:345.45
EINECS:
Product Categories:
Mol File:1782099-36-8.mol
XLR11 N-(4-hydroxypentyl) metabolite (CRM) Structure
XLR11 N-(4-hydroxypentyl) metabolite (CRM) Chemical Properties
Boiling point 490.0±40.0 °C(Predicted)
density 1.14±0.1 g/cm3(Predicted)
pka13.88±0.20(Predicted)
Safety Information
MSDS Information
XLR11 N-(4-hydroxypentyl) metabolite (CRM) Usage And Synthesis
DescriptionXLR11 is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor.1 XLR11 also has an N-(5-fluoropentyl) chain, which increases binding to both CB receptors.2 XLR11 N-(4-hydroxypentyl) metabolite is an expected phase I metabolite of XLR11, based on the known metabolism of similar compounds.3,4 The physiological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Uses4-Hydroxypentyl XLR11 is a metabolite of XLR11 (X746300), an aminoalkylindole compound that is expected to be a cannabinoid (CB) mimetic.
DefinitionChEBI: XLR11 N-(4-hydroxypentyl) metabolite is a member of indoles.
References1. Frost, J.M., Dart, M.J., Tietje, K.R., et al. Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity J. Med. Chem. 53(1),295-315(2010).
2. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives US7241799B2,(2001).
3. Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS Anal. Bioanal. Chem. 386(5),1345-1355(2006).
4. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
XLR11 N-(4-hydroxypentyl) metabolite (CRM) Preparation Products And Raw materials
Tag:XLR11 N-(4-hydroxypentyl) metabolite (CRM)(1782099-36-8) Related Product Information
XLR11 N-(2-fluoropentyl) isomer XLR11 N-(4-pentenyl) analog XLR11 6-hydroxyindole metabolite XLR11 Degradant XLR11 N-(3-fluoropentyl) isomer XLR12