XLR11 6-hydroxyindole metabolite

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CAS:1630022-98-8
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CAS:1630022-98-8
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CAS:1630022-98-8
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Products Intro: Product Name:XLR11 6-hydroxyindole metabolite
CAS:1630022-98-8
XLR11 6-hydroxyindole metabolite Basic information
Product Name:XLR11 6-hydroxyindole metabolite
Synonyms:XLR11 6-hydroxyindole metabolite;OZGNIKIHSWKZFS-UHFFFAOYSA-N;Methanone, [1-(5-fluoropentyl)-6-hydroxy-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-;1-(5-fluoropentyl)-6-hydroxy-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone
CAS:1630022-98-8
MF:C21H28FNO2
MW:345.45
EINECS:
Product Categories:
Mol File:1630022-98-8.mol
XLR11 6-hydroxyindole metabolite Structure
XLR11 6-hydroxyindole metabolite Chemical Properties
Boiling point 484.8±35.0 °C(Predicted)
density 1.14±0.1 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
form A crystalline solid
pka9.82±0.40(Predicted)
Safety Information
MSDS Information
XLR11 6-hydroxyindole metabolite Usage And Synthesis
DescriptionXLR11 is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor.1 XLR11 also has an N-(5-fluoropentyl) chain, which increases binding to both CB receptors.2 XLR11 6-hydroxyindole metabolite is an expected minor monohydroxylated urinary metabolite of XLR11.3 The biological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
References1. Frost, J.M., Dart, M.J., Tietje, K.R., et al. Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity J. Med. Chem. 53(1),295-315(2010).
2. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives US7241799B2,(2001).
3. Wintermeyer, A., M?ller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
XLR11 6-hydroxyindole metabolite Preparation Products And Raw materials
Tag:XLR11 6-hydroxyindole metabolite(1630022-98-8) Related Product Information
XLR11 N-(2-fluoropentyl) isomer XLR11 N-(4-pentenyl) analog XLR11 Degradant XLR11 N-(4-hydroxypentyl) metabolite (CRM) XLR11 N-(3-fluoropentyl) isomer XLR12