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SUFENTANIL CITRATE

SUFENTANIL CITRATE Basic information
Product Name:SUFENTANIL CITRATE
Synonyms:SUFENTANIL CITRATE;n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-n-phenylpropionam;n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)-propionanilidcitr;n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilidecitrat;r30730citratesalt;r33800;sufentanylcitrate;N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamide citrate
CAS:60561-17-3
MF:C28H38N2O9S
MW:578.68
EINECS:262-295-4
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Organics
Mol File:60561-17-3.mol
SUFENTANIL CITRATE Structure
SUFENTANIL CITRATE Chemical Properties
Melting point 96.60C
Fp 9℃
storage temp. -20°C Freezer
solubility H2O: soluble1mg/mL, clear
form powder
color white to beige
Stability:Hygroscopic
Safety Information
Hazard Codes T+,T,F
Risk Statements 26/27/28-39/23/24/25-23/24/25-11
Safety Statements 26-27-28-36/37/39-45-36/37-16-7
RIDADR 3249
WGK Germany 3
HazardClass 6.1(b)
PackingGroup III
HS Code 2934910000
ToxicityLD50 intravenous in dog: 14100ug/kg
MSDS Information
SUFENTANIL CITRATE Usage And Synthesis
Chemical PropertiesCrystalline Solid
UsesPotent derivative of Fentanyl. Analgesic (narcotic). Controlled substance (opiate)
DefinitionChEBI: Sufentanil citrate is an anilide.
Brand nameSufenta (Akorn).
General DescriptionSufentanil is a short acting synthetic opioid analgesic most commonly used for pain relief during medical operations. This certified solution standard is applicable to use in clinical toxicology, pain prescription monitoring, or forensic analysis by LC-MS/MS or GC/MS. Sufentanil is sold under the trade name Sufenta.
Clinical UseAddition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity. The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its greater sedative and analgesic potency, sufentanil produces less respiratory depression at effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short duration is caused by redistribution from brain tissues after intravenous dosage.
Veterinary Drugs and TreatmentsAn opioid analgesic, sufentanil may be useful as an anesthesia adjunct or as an epidural analgesic. In humans, it has been used as the primary anesthetic in intubated patients with assisted ventilation, and as a post-operative analgesic.
SUFENTANIL CITRATE Preparation Products And Raw materials
Tag:SUFENTANIL CITRATE(60561-17-3) Related Product Information
2-Thiophenemethylamine N-Phenyl-N-(4-piperidinyl)propanamide admixture with HCl salt N-(1-METHYLPIPERIDIN-4-YL)ANILINE 2-DIMETHYLAMINO-2-METHYL-1-PROPANOL SUFENTANIL CITRATE Ammonium citrate dibasic 4-ACETAMIDOPIPERIDINE N,N-Dimethylpiperidin-4-amine 1-Methyl-4-(methylamino)piperidine FENTANYL 4-AMINO-1-(1-PROPYL)-PIPERIDINE N-METHYL-N-4-PIPERIDINYLACETAMIDE Sufentanil N-phenylpiperidin-4-amine 1-ETHYL-PIPERIDIN-4-YLAMINE Isopropylamine, 2-(methoxymethyl)- METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE CHEMBRDG-BB 4010868