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| | 2-Chloro-4-fluorobenzonitrile Basic information |
| | 2-Chloro-4-fluorobenzonitrile Chemical Properties |
| Melting point | 64-66 °C(lit.) | | Boiling point | 233.4±20.0 °C(Predicted) | | density | 1.3760 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | powder to crystal | | color | White to Almost white | | BRN | 6323034 | | InChI | InChI=1S/C7H3ClFN/c8-7-3-6(9)2-1-5(7)4-10/h1-3H | | InChIKey | PGKPNNMOFHNZJX-UHFFFAOYSA-N | | SMILES | C(#N)C1=CC=C(F)C=C1Cl | | CAS DataBase Reference | 60702-69-4(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Chloro-4-fluorobenzonitrile(60702-69-4) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-36-36/37/39 | | RIDADR | 3439 | | WGK Germany | 3 | | Hazard Note | Harmful/Irritant | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29269090 |
| | 2-Chloro-4-fluorobenzonitrile Usage And Synthesis |
| Description | 2-Chloro-4-fluorobenzonitrile is an organohalogen compound that can be used for aryl dechlorination and defluorination reactions using organic super photoreductants. The use of a light emitting diode to directly excite the super electron donor tetrakis(dimethylamino)ethylene (TDAE) at 440 or 390 nm provides a quantitative reductant capable of reducing aryl chlorides and fluorides. The photoactive excited state lifetime of TDAE in cyclohexane is 17.3 ns at room temperature, with an oxidation potential of about -3.4 V for SCE. | | Chemical Properties | semi-transparent crystalline chunks | | Uses | 2-Chloro-4-fluorobenzonitrile may be used in the preparation of 2-chloro-3,4-diaminobenzonitrile. | | Uses | 4-Fluoro-2-chlorobenzonitrile is used in the synthesis of androgen receptor antagonists in the treatment of prostate cancer. Also used in the synthesis of pyrazole derivatives as novel androgen receptor antagonists. |
| | 2-Chloro-4-fluorobenzonitrile Preparation Products And Raw materials |
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