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L-Isoserine

L-Isoserine Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-(0)57185586718 +86-13336195806
Email: sales@capot.com
Products Intro: Product Name:L-isoserine
CAS:632-13-3
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:L-Isoserine
CAS:632-13-3
Purity:99% Package:100g ;1KG ;5KG 25KG
Company Name: Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel: 0523-86132544
Email: sales@thbiochem.com
Products Intro: Product Name:L-Isoserine
CAS:632-13-3
Purity:99% Package:10g;100g;1Kg;25kg
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:632-13-3
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:L-Isoserine
CAS:632-13-3
Purity:0.99 Package:5KG;1KG

L-Isoserine manufacturers

  • L-Isoserine
  • L-Isoserine pictures
  • $0.00/ kg
  • 2024-12-25
  • CAS:632-13-3
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 1T+
  • L-Isoserine
  • L-Isoserine pictures
  • $1.00 / 1KG
  • 2020-01-05
  • CAS:632-13-3
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
L-Isoserine Basic information
Product Name:L-Isoserine
Synonyms:(S)-ISOSERINE;(S)-2-HYDROXY-B-ALANINE;(S)-2-HYDROXY-BETA-ALANINE;(S)-3-AMINO-2-HYDROXYPROPIONIC ACID;L-ISOSERINE;(s)-2-hydroxy-β-alanine;(S)-LSOSERINE;(2S)-3-AMINO-2-HYDROXY-PROPANOIC ACID
CAS:632-13-3
MF:C3H7NO3
MW:105.09
EINECS:
Product Categories:(intermediate of isepamicin)
Mol File:632-13-3.mol
L-Isoserine Structure
L-Isoserine Chemical Properties
Melting point 199~201℃
Boiling point 386.6±27.0 °C(Predicted)
density 1.415±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pkapK1:2.72(+1);pK2:9.25(0) (25°C,μ=0.16)
color White to Almost white
Water Solubility Slightly soluble in water.
Sensitive Moisture Sensitive
InChIInChI=1S/C3H7NO3/c4-1-2(5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChIKeyBMYNFMYTOJXKLE-REOHCLBHSA-N
SMILESC(O)(=O)[C@@H](O)CN
CAS DataBase Reference632-13-3(CAS DataBase Reference)
Safety Information
WGK Germany 3
10-21
HS Code 2922500090
MSDS Information
ProviderLanguage
SigmaAldrich English
L-Isoserine Usage And Synthesis
UsesIt is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Biological ActivityResearch has found that L-isoserine showed the ability to inhibit Aminopeptidase N (APN) at a half-maximal inhibitory concentration (IC50 ) value of 563 μM, which could serve as a new lead compound for further chemical modification and optimization. In addition, it has been reported that L-isoserine-L-leucine dipeptide shows moderate aminopeptidase B inhibitory activity (IC50 of 140 μM). This evidence indicates that the incorporation of an amino acid to L-isoserine may contribute to its inhibitory activity against APN.  L-isoserine induces long-lasting effects by increasing the expression of GAT3 (glial GABA transporte) in peri-infarct regions[1-2].
References[1] Yang K , et al. Synthesis of a novel series of L-isoserine derivatives as aminopeptidase N inhibitors. Journal of Enzyme inhibition and Medicinal Chemistry, 2011; 27: 302-310.
[2] Lie M , et al. GAT3 selective substrate l-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice. Journal of Cerebral Blood Flow & Metabolism, 2017; 39.
L-Isoserine Preparation Products And Raw materials
Tag:L-Isoserine(632-13-3) Related Product Information
DL-2-AMINOPROPIONIC ANHYDRIDE DL-ISOSERINE,DL-ISOSERINE 99+% (2r,3s)-n-tert-butoxycarbonyl-3-phenyl-isoserine methyl ester,METHYL (2R,3S)-N-BOC-3-PHENYL ISOSERINE FMOC-DL-ISOSERINE,N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-DL-ISOSERINE (S)-IsoserineL-Isoserine,(R)-ISOSERINE ISOSERINE, N-BETA-T-BUTOXYCARBONYL-DL-ISOSERINE N-(T-BOC)-3-PHENYL ISOSERINE ETHYL ESTER D-Isoserine Isoserine, N,N-dimethyl- (6CI) FMOC-ISOSERINE 2R,3S-N-BENZOYLPHENYL ISOSERINE ( TAXOL SIDE CHAI Isoserine, N-glycyl- (3CI) BOC-ISOSERINE ISOSERINE BOC-ISOSERINE, Isoserine, N-2-pyridyl-, methyl ester, DL- (6CI) N-boca mino phenyl isoserine