| Company Name: |
AlliChem, LLC
|
| Tel: |
301-317-5072 |
| Email: |
sales@allichemllc.com |
| Products Intro: |
|
|
| | DIPERODON Basic information |
| Product Name: | DIPERODON | | Synonyms: | 1,2-PROPANEDIOL,3-(1-PIPERIDINYL)-,BIS(PHENYLCARBAMATE)(ESTER);3-Piperidino-1,2-propanediol bis(N-phenylcarbamate);Bis(N-phenylcarbamic acid) 3-piperidino-1,2-propanediyl;Bis(N-phenylcarbamic acid)3-piperidino-1,2-propanediyl ester;Diothane;Diperodone;(piperidinomethyl)ethylene dicarbanilate;DIPERODON | | CAS: | 101-08-6 | | MF: | C22H27N3O4 | | MW: | 397.47 | | EINECS: | 202-913-1 | | Product Categories: | | | Mol File: | 101-08-6.mol |  |
| | DIPERODON Chemical Properties |
| Boiling point | 520.91°C (rough estimate) | | density | 1.2228 (rough estimate) | | refractive index | 1.6500 (estimate) | | pka | pKa 8.44(H2O) (Occasionally) |
| | DIPERODON Usage And Synthesis |
| Originator | Diothane Hydrochloride,HMR | | Definition | ChEBI: N-phenylcarbamic acid [2-[anilino(oxo)methoxy]-3-(1-piperidinyl)propyl] ester is a carbamate ester. | | Manufacturing Process | 15.0 g phenylisocyanate in 100 ml of anhydrous ether are added to 10 g of N-
(1,2-dihydroxypropyl)-piperidine (prepared from glycide and piperidine) and
the solution boiled for two hours, after which it is cooled and saturated with
dry hydrogen chloride gas. The ether layer is then decanted off and the
remaining insoluble product is dissolved in a hot mixture of acetone and ethyl
acetate which on cooling precipitates white crystals of the hydrochloride of the
ester of 1,2-propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate); MP 197°-
198°C. A base form may be prepared by adding an equivalent of triethyl
amine. | | Therapeutic Function | 1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate)
(ester), hydrochloride |
| | DIPERODON Preparation Products And Raw materials |
|