N-Nitroso-N-Methyl-4-Aminobutyric Acid manufacturers
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| | N-Nitroso-N-Methyl-4-Aminobutyric Acid Basic information |
| Product Name: | N-Nitroso-N-Methyl-4-Aminobutyric Acid | | Synonyms: | N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID;4-(methylnitrosoamino)-butyricaci;4-(n-nitroso-n-methylamino)butyricacid;n-methyl-n-(3-carboxypropyl)nitrosamine;4-(N-NITROSOMETHYLAMINO)BUTYRICACID;Losartan Impurity 17;Azilsartan Impurity 102;N-Nitroso-N-methyl-4-aminobutyric Acid (200 μg/mL in Methanol) | | CAS: | 61445-55-4 | | MF: | C5H10N2O3 | | MW: | 146.14 | | EINECS: | | | Product Categories: | Aliphatics;Nicotine Derivatives | | Mol File: | 61445-55-4.mol |  |
| | N-Nitroso-N-Methyl-4-Aminobutyric Acid Chemical Properties |
| Melting point | >25 °C | | Boiling point | 265.74°C (rough estimate) | | density | 1.3394 (rough estimate) | | refractive index | 1.4954 (estimate) | | storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere | | solubility | Chloroform (Soluble), Dichloromethane (Slightly), Ethyl Acetate (Slightly) | | form | Solid | | pka | 4.57±0.10(Predicted) | | color | Off-White to Yellow | | Stability: | Hygroscopic |
| | N-Nitroso-N-Methyl-4-Aminobutyric Acid Usage And Synthesis |
| Chemical Properties | Yellow Oil | | Uses | N-Nitroso-N-methyl-4-aminobutyric acid EP reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.
It is also used to prepare N-Nitrosamines spiking solution to detect the concentration of N-nitrosamines in active substances by liquid chromatography coupled with mass spectrometry according to the monograph 20542of European Pharmacopoeia. | | Definition | ChEBI: N-nitroso-N-methyl-4-aminobutyric acid is a nitrosamine that has methyl and 3-carboxypropyl substituents. It is a tobacco-derived nitrosamino acid that is a known animal and potential human carcinogen. It induces bladder transitional cell carcinomas in rats and has recently been identified as a contaminant in certain blood pressure medications. It has a role as a carcinogenic agent, a rat metabolite, a xenobiotic metabolite and a plant metabolite. It is a monocarboxylic acid and a nitrosamine. |
| | N-Nitroso-N-Methyl-4-Aminobutyric Acid Preparation Products And Raw materials |
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