| Company Name: |
Beijing Comparison Pharmaceutical Technology Co., Ltd
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010-010-52878169 15801002657 |
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sales@bjcomparison.com |
| Products Intro: |
Product Name:2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-bromo-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
CAS:91160-89-3
Purity:>=98% Package:100mg
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| Company Name: |
ChemStrong Scientific Co.,Ltd
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| Tel: |
0755-0755-66853366 13670046396 |
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sales@chem-strong.com |
| Products Intro: |
Product Name:Prednisone Impurity 5
CAS:91160-89-3
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Jinan blalong chemical co. LTD
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| Tel: |
2710913286@.com |
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1513643261@qq.com |
| Products Intro: |
Product Name:PrednisoneImpurity13
CAS:91160-89-3
Purity:99% HPLC Package:50G;10G;1G;500MG;100MG
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| | Prednisone Impurity 13 Basic information |
| Product Name: | Prednisone Impurity 13 | | Synonyms: | Prednisone Impurity 13;9α-bromo-11β,16α,17α,21-tetrahydroxypregnane-1,4-diene-3,20-dione-21-acetate;BNKY015-BD02;(11β,16α)-21-(Acetyloxy)-9-bromo-11,16,17-trihydroxy-pregna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-bromo-11,16,17-trihydroxy-, (11β,16α)-;9α-bromo-11β,16α,17α,21-tetrahydroxypregnane-1,4-diene-3,20-dione-21-acetate;Prednisone Impurity 5;Budesonide Impurity 53 | | CAS: | 91160-89-3 | | MF: | C23H29BrO7 | | MW: | 497.38 | | EINECS: | | | Product Categories: | | | Mol File: | 91160-89-3.mol |  |
| | Prednisone Impurity 13 Chemical Properties |
| Boiling point | 636.3±55.0 °C(Predicted) | | density | 1.53±0.1 g/cm3(Predicted) | | pka | 11.57±0.70(Predicted) |
| | Prednisone Impurity 13 Usage And Synthesis |
| Uses | (11β,16α)-21-(Acetyloxy)-9-bromo-11,16,17-trihydroxy-pregna-1,4-diene-3,20-dione is used as a reactant in the synthesis of triamcinolone acetonide, a synthetic corticosteroid used to treat skin conditions. | | Synthesis |
50.5 g of 2-((8S,10S,13S,14S,16R,17S)-16,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate was dissolved in 1500 ml of acetone, 70 ml of 5% perchloric acid was added, the temperature was lowered to 0°C with stirring, and 45 g of N-bromosuccinimide was added and stirred After the reaction was completed, 50 ml of 20% sodium sulfite aqueous solution was added, the acetone was concentrated, the water was separated, filtered, and dried to obtain 62 g of Prednisone Impurity 13 (9α-bromo-11β,16α,17α,21-tetrahydroxypregnane-1,4-diene-3,20-dione-21-acetate).
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| | Prednisone Impurity 13 Preparation Products And Raw materials |
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