- LY 303511
-
- $1.00 / 1KG
-
2019-12-20
- CAS:154447-38-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kgs
|
| | LY 303511 Basic information |
| Product Name: | LY 303511 | | Synonyms: | 2-(1-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one;8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one;8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one LY303511;LY303511, >=98%;LY 303511; LY303511;4H-1-Benzopyran-4-one, 8-phenyl-2-(1-piperazinyl)-;LY-303511(Nv-128) | | CAS: | 154447-38-8 | | MF: | C19H18N2O2 | | MW: | 306.36 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 154447-38-8.mol |  |
| | LY 303511 Chemical Properties |
| Boiling point | 496.1±45.0 °C(Predicted) | | density | 1.237±0.06 g/cm3(Predicted) | | storage temp. | Store at +4°C | | solubility | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO | | form | Amber solid | | pka | 9.20±0.10(Predicted) |
| | LY 303511 Usage And Synthesis |
| Uses | LY 303511 is an inactive analog of the phosphoinositide 3-kinase inhibitor LY294002. | | Definition | ChEBI: 8-phenyl-2-(1-piperazinyl)-1-benzopyran-4-one is a N-arylpiperazine. | | Biological Activity | Negative control compound with respect to LY 294004 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-onehydrochloride ) PI 3-kinase inhibitory activity. Blocks voltage-gated potassium (K v ) channels (IC 50 = 64.6 μ M) and inhibits IL-1 β -stimulated NF- κ B activation, attenuating MCP-1 expression. Anti-proliferative. |
| | LY 303511 Preparation Products And Raw materials |
|