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| | C2 DIHYDROCERAMIDE Basic information |
| | C2 DIHYDROCERAMIDE Chemical Properties |
| Melting point | 118-119°C | | Boiling point | 531.8±40.0 °C(Predicted) | | density | 0.953±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Soluble in DMSO (up to 5 mg/ml, with warming). | | pka | 14.27±0.20(Predicted) | | form | White solid | | color | White | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week. |
| | C2 DIHYDROCERAMIDE Usage And Synthesis |
| Description | C2 Dihydroceramide (13031-64-6) is a negative control for C2-ceramide (cat.# 10-1181).1,2 Induces autophagy in a variety of cell types.3,4 | | Chemical Properties | C2 DIHYDROCERAMIDE is White Solid | | Uses | C2 DIHYDROCERAMIDE may be used as a negative control for C2 Ceramide | | Uses | May be used as a negative control for C2 Ceramide. | | Definition | ChEBI: A dihydroceramide in which the ceramide acyl group is specified as acetyl. | | References | 1) Bielawska et al. (1993) Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide; J. Biol. Chem. 268 26226
2) Obeid et al. (1993) Programmed cell death induced by ceramide; Science, 259 1769
3) Jiang et al. (2012) Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide; Int. J. Cancer, 130 685
4) Siddique et al. (2015) Dihydroceramides: From Bit Players to Lead Actors; J. Biol. Chem., 290 15371 |
| | C2 DIHYDROCERAMIDE Preparation Products And Raw materials |
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