Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:3-MATIDA;α-AMino-5-carboxy-3-Methyl-2-thiopheneaceticacid CAS:518357-51-2 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
|
|
| 3-MATIDA Basic information |
Product Name: | 3-MATIDA | Synonyms: | 3-MATIDA;ALPHA-AMINO-5-CARBOXY-3-METHYL-2-THIOPHENEACETIC ACID;α-Amino-5-carboxy-3-methyl-2-thiopheneaceticacid;5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid;2-Thiopheneacetic acid, α-amino-5-carboxy-3-methyl-;3 MATIDA,3MATIDA | CAS: | 518357-51-2 | MF: | C8H9NO4S | MW: | 215.23 | EINECS: | | Product Categories: | Glutamate receptor | Mol File: | 518357-51-2.mol | ![3-MATIDA Structure](CAS/GIF/518357-51-2.gif) |
| 3-MATIDA Chemical Properties |
storage temp. | Store at +4°C | solubility | Soluble to 100 mM in 1eq. NaOH and to 50 mM in DMSO | form | Powder |
| 3-MATIDA Usage And Synthesis |
Uses | 3-MATIDA is a potent mGluR-1 antagonist. | Definition | ChEBI: 5-[amino(carboxy)methyl]-4-methyl-2-thiophenecarboxylic acid is an alpha-amino acid. | Biological Activity | Potent metabotropic glutamate mGlu 1 receptor antagonist (IC 50 = 6.3 μ M at rat mGlu 1a ). Displays ≥ 40-fold selectivity over other receptors: mGlu 5 , mGlu 2 , mGlu 4a (IC 50 > 300 μ M), NMDA and AMPA (IC 50 = 250 μ M). Neuroprotective in cultured murine cortical cells and rat hippocampal slice cultures in vitro . Reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo . |
| 3-MATIDA Preparation Products And Raw materials |
|