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Althiazide

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Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-81148696 +86-15536356810
Email: 1022@dideu.com
Products Intro: Product Name:Althiazide
CAS:5588-16-9
Purity:99.0% Package:1KG;|25KG
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
CAS:5588-16-9
Purity:0.99 Package:5KG;1KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Altizide；Aldactacine;P1779;CB-8093;CB 8093;P-1779;P 1779
CAS:5588-16-9
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: LEAPCHEM CO., LTD.
Tel: +86-852-30606658
Email: market18@leapchem.com
Products Intro: Product Name:6-CHLORO-3,4-DIHYDRO-3-[(2-PROPENYLTHIO)METHYL]-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
CAS:5588-16-9
Purity:0 Package:1g; 5g; 25g; 1kg; 5kg; 25kg Remarks:0
Company Name: Cochemical Co. Ltd.
Tel: +86-029-86115547 +86-17791676824
Email: sales@cochemical.com
Products Intro: Product Name:3-((allylthio)methyl)-6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
CAS:5588-16-9
Purity:0.97 Package:5KG;1KG;100g;25g;10g;5g

Althiazide manufacturers

  • Altizide
  • Altizide pictures
  • $1980.00 / 50mg
  • 2024-10-24
  • CAS:5588-16-9
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
  • Althiazide
  • Althiazide pictures
  • $0.00 / 1KG
  • 2024-08-02
  • CAS:5588-16-9
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 1000kg
Althiazide Basic information
Product Name:Althiazide
Synonyms:ALTHIAZIDE;6-CHLORO-3,4-DIHYDRO-3-[(2-PROPENYLTHIO)METHYL]-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE;3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;P-1779;3-[(allylthio)methyl]-6-chloro-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;6-Chloro-3,4-dihydro-3-[(2-propen-1-ylthio)Methyl]-2H-1,2,4-benzothiadiazine-7-sulfonaMide 1,1-Dioxide;Althizide
CAS:5588-16-9
MF:C11H14ClN3O4S3
MW:383.89
EINECS:226-994-8
Product Categories:Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium
Mol File:5588-16-9.mol
Althiazide Structure
Althiazide Chemical Properties
Melting point 206-207°
Boiling point 625.8±65.0 °C(Predicted)
density 1.502±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Practically insoluble in water, soluble in methanol, practically insoluble in dichloromethane.
pka8.33±0.40(Predicted)
color White to Off-White
EPA Substance Registry System2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide (5588-16-9)
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
Althiazide Usage And Synthesis
DescriptionAlthiazide, also known as altizide, is an agent belonging to the class of thiazide diuretics with antihypertensive activity. This aldosterone antagonist is often combined with spironolactone.
Chemical PropertiesWhite Solid
OriginatorAlthiazide,Solchem
UsesDiuretic and antihypertensive.
DefinitionChEBI: Althiazide is a benzothiadiazine. It is the thiazide and sulfonamide derivative.
Manufacturing ProcessTo 6.75 g (0.0225 mole) of 4-amino-2-chloro-5-(methylsulfamyl) benzenesulfonamide in 45 ml of dimethylformamide is added 4.86 g (0.03 mole) of dimethyl allylmercaptoacetal followed by 1.5 ml ethyl acetate saturated with hydrogen chloride gas. The solution is refluxed for 1.5 hours, cooled and added dropwise with stirring to ice/water. The resulting precipitate is filtered, dried and recrystallized from isopropanol. The recrystallization gave 4.0 g of 2-methyl-3-allylthiomethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4- benzothiadiazine-1,1-dioxide; M.P. 168.5-170°C.
Therapeutic FunctionDiuretic, Antihypertensive
Tag:Althiazide(5588-16-9) Related Product Information
o-Chlorobenzenesulfonamide Benzenesulfonamide, 2-(methylamino)- (9CI) 4-Chloro-N-methylbenzenesulphonamide Althiazide Hydrochlorothiazide 2-Aminobenzenesulfonamide 4-Chlorobenzenesulfonamide CLOFENAMIDE 4-Amino-6-chlorobenzene-1,3-disulfonamide Methalthiazide 2-AMINO-N-METHYLBENZENESULFONAMIDE 4-CHLORO-1,3-BENZENEDITHIOL