- Picroside I
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- $50.00 / 20mg
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2024-11-19
- CAS:27409-30-9
- Min. Order:
- Purity: 99.43%
- Supply Ability: 10g
- Picroside I
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- $0.00 / 20mg
-
2023-02-24
- CAS:27409-30-9
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- PICROSIDE I
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- $1.00 / 1g
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2019-12-20
- CAS:27409-30-9
- Min. Order: 1g
- Purity: 99%
- Supply Ability: KG/T
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| | PICROSIDE I Basic information |
| Product Name: | PICROSIDE I | | Synonyms: | PICROSIDE I;beta-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha]]-;Picroside-Ⅰ;6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-;β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-;[1aS-[1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha]]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl 6-(3-phenyl-2-propenoate) beta-D-glucopyranoside;β-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-;PICOLINIC ACID(P) | | CAS: | 27409-30-9 | | MF: | C24H28O11 | | MW: | 492.47 | | EINECS: | 248-445-1 | | Product Categories: | Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 27409-30-9.mol |  |
| | PICROSIDE I Chemical Properties |
| Boiling point | 778.6±60.0 °C(Predicted) | | density | 1.56±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | ethanol: soluble1mg/mL, clear, colorless | | form | powder | | pka | 12.70±0.70(Predicted) | | color | White | | InChIKey | BSYHSWKTXMTFNF-NTLZGZQOSA-N |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29389090 |
| | PICROSIDE I Usage And Synthesis |
| Description | Picroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas. Picroside I is an iridoid glycoside found in picroliv. By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver. Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM. At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein. | | Uses | Picroside I acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis. | | in vivo | Picroside I (20 mg/kg, o.p, 12 d) reduces AHR in the experimental asthma model and reduces OVA-associated IgE levels[2].
| Animal Model: | Ovalbumin (OVA) systematic sensitization BALB/c mice model[2] | | Dosage: | 0.2, 2.0 and 20 mg/kg
| | Administration: | Orally, once daily, from day 20 to day 32
| | Result: | Inhibited allergen-triggered inflammatory cell infiltration. |
| | IC 50 | STAT6 |
| | PICROSIDE I Preparation Products And Raw materials |
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