Company Name: |
Xi'an Qiyue Biotechnology Co., Ltd.
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Tel: |
400-400-6966-012-012 17778955912 |
Email: |
2957605606@qq.com |
Products Intro: |
Product Name:Tos-PEG2-NH2 CAS:1246286-33-8 Package:5mg
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Company Name: |
Aobolihui
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Tel: |
0917-18691729 18691729963 |
Email: |
2553382659@qq.com |
Products Intro: |
Product Name:2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate CAS:1246286-33-8 Purity:99% Package:5KG;1KG
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| PROTAC Linker 27 Basic information |
Product Name: | PROTAC Linker 27 | Synonyms: | PROTAC Linker 27;Tos-PEG2-NH2;2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate;Ethanol, 2-(2-aminoethoxy)-, 1-(4-methylbenzenesulfonate) | CAS: | 1246286-33-8 | MF: | C11H17NO4S | MW: | 259.32 | EINECS: | | Product Categories: | peg | Mol File: | 1246286-33-8.mol | |
| PROTAC Linker 27 Chemical Properties |
Boiling point | 414.5±30.0 °C(Predicted) | density | 1?+-.0.06 g/cm3(Predicted) | pka | 8?+-.0.10(Predicted) |
| PROTAC Linker 27 Usage And Synthesis |
Biological Activity | Tos-PEG2-NH2 (PROTAC Linker 27) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
| PROTAC Linker 27 Preparation Products And Raw materials |
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