| Company Name: |
YJ Pharma Gold
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| Tel: |
0513-15251351988 15251351988 |
| Email: |
3686954964@qq.com |
| Products Intro: |
Product Name:(S)-11-benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid
CAS:2264011-98-3
Purity:99% Package:5g;10g;500g；1kg
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| Company Name: |
Hygeia (Chengdu) pharmaceutical technique Co., Ltd
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| Tel: |
028-84502008 13568869383 |
| Email: |
sales@hygeiapharm.com |
| Products Intro: |
Product Name:(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid
CAS:2264011-98-3
Purity:98%+ Package:5g;25g;1000g
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| Company Name: |
Zhengzhou Huiju Chemical Co., Ltd.
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| Tel: |
0371-55900031 18137872243 |
| Email: |
2853979815@qq.com |
| Products Intro: |
Product Name:(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid
CAS:2264011-98-3
Purity:98% Package:100mg ；500mg ；1g ；5g ；10g ；25g ；50g ；100g ；250g ；500g ；1kg ；5kg
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| Company Name: |
Abydos Scientific
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| Tel: |
025-84767922 18936879710 |
| Email: |
sales@abydoscientific.com |
| Products Intro: |
Product Name:(S)-11-benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid
CAS:2264011-98-3
Purity:99% Package:5kg;1kg;100g
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| | (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid Basic information |
| Product Name: | (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid | | Synonyms: | (S)-11-benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid;Fmoc-GGFG-Glycolic acid;(S)-10-Benzyl-16-(Fmoc-amino)-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-1-oic Acid;Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH;Fmoc-Gly-Gly-L-Phe-N-[(carboxymethoxy)methyl]Glycinamide | | CAS: | 2264011-98-3 | | MF: | C33H35N5O9 | | MW: | 645.67 | | EINECS: | | | Product Categories: | | | Mol File: | 2264011-98-3.mol |  |
| | (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid Chemical Properties |
| Boiling point | 1107.2±65.0 °C(Predicted) | | density | 1.339±0.06 g/cm3(Predicted) | | pka | 3.20±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid Usage And Synthesis |
| Uses | Fmoc-GGFG-Glycolic acid ((S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid) is a cleavable ADC linker with an Fmoc group and a terminal carboxylic acid group. | | Preparation | benzyl(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid (150 mg，0.2 mmol), methanol (8mL), and DMF (1mL) were added to the single-mouth bottle, and then Pd/C (45mg, 5%) was added for hydrogenation reaction for 2 hours. After filtration, 1.8 mL of diethylamine was added to the filtrate, and the mixture was stirred at room temperature for 2 hours. The crude product is obtained by reducing pressure concentration. Finally, (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid was obtained after purification.
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| | (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9,12,15-pentaoxo-2,18-dioxa-4,7,10,13,16-pentaazaicosan-20-oic acid Preparation Products And Raw materials |
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