Company Name: |
TargetMol Chemicals Inc.
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15002134094 |
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marketing@targetmol.cn |
Products Intro: |
Product Name:Fendiline CAS:13042-18-7 Purity:详情请点击官网 Package:1 mg
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| Fendiline Basic information |
Product Name: | Fendiline | Synonyms: | N-(1-Phenylethyl)-3,3-diphenylpropylamine;3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)- | CAS: | 13042-18-7 | MF: | C23H25N | MW: | 315.45 | EINECS: | 235-915-6 | Product Categories: | | Mol File: | 13042-18-7.mol | ![Fendiline Structure](CAS/GIF/13042-18-7.gif) |
| Fendiline Chemical Properties |
Boiling point | bp0.3 206-210° | density | 1.031±0.06 g/cm3(Predicted) | pka | 9.49±0.28(Predicted) | Water Solubility | 2.331mg/L(22.5 ºC) |
| Fendiline Usage And Synthesis |
Originator | Sensit,Thiemann,W. Germany,1974 | Definition | ChEBI: 3,3-diphenyl-N-(1-phenylethyl)-1-propanamine is a diarylmethane. | Manufacturing Process | 21.13 grams of γ,γ-diphenyl-propylamine and 12.01 grams of acetophenone
are hydrogenated in 200 ml of methanol at 55°C and a pressure of 10
atmospheres in the presence of palladium charcoal. On filtration of the
catalyst the solution is concentrated and the remainder is distilled in vacuo at
a pressure of 0.3 Hg mm. The main distillate is collected at 206° to 210°C.
25.38 grams of N-[1'-phenylethyl-(1')]-1,1-diphenyl-propyl-(3)-amine are
obtained. The product is dissolved in 134 ml of 96% ethanol whereupon 26.8 ml of
concentrated hydrochloric acid and 201 ml of water are added while cooling
with ice-water. The precipitate is filtered off and dried in vacuo at 100°C.
22.98 grams of N-[1'-phenylethyl)-(1')]-1,1-diphenyl-propyl-(3)-amine
hydrochloride are obtained. MP 200° to 201°C. On recrystallization from 285
ml of a 2:1 mixture of water and 96% ethanol the melting point remains
unchanged. | Therapeutic Function | Coronary vasodilator |
| Fendiline Preparation Products And Raw materials |
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