- Ilaprazole
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- $1.00 / 1kg
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2024-07-01
- CAS:172152-36-2
- Min. Order: 0.1kg
- Purity: 98%
- Supply Ability: 50kg
- Ilaprazole
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- $36.00 / 1kg
-
2024-04-29
- CAS:172152-36-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Ilaprazole
-
- $0.00 / 1KG Ton
-
2023-09-08
- CAS:172152-36-2
- Min. Order: 1KG Ton
- Purity: 99%+
- Supply Ability: 2 tons/month
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| | Ilaprazole Basic information |
| Product Name: | Ilaprazole | | Synonyms: | 2-[(4-methoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-5-pyrrol-1-yl-3H-benzoimidazole;2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-1H-benzimidazole;IY 81149;Ilaprazole(IY 81149);1H-BenziMidazole,2-[[(4-Methoxy-3-Methyl-2-pyridinyl)Methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole;IY81149; IY-81149; IY 81149;Ilaprazole USP/EP/BP | | CAS: | 172152-36-2 | | MF: | C19H18N4O2S | | MW: | 366.44 | | EINECS: | 1308068-626-2 | | Product Categories: | 172152-36-2 | | Mol File: | 172152-36-2.mol |  |
| | Ilaprazole Chemical Properties |
| Boiling point | 651.0±65.0 °C(Predicted) | | density | 1.39 | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMF: 10mg/mL; DMSO: 15mg/mL; DMSO:PBS (pH 7.2) (1:7): 0.12mg/mL; Ethanol: 0.3mg/mL | | form | A solid | | pka | 8.23±0.10(Predicted) | | color | Off-white to gray | | InChI | InChI=1S/C19H18N4O2S/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23/h3-11H,12H2,1-2H3,(H,21,22) | | InChIKey | HRRXCXABAPSOCP-UHFFFAOYSA-N | | SMILES | C1(S(CC2=NC=CC(OC)=C2C)=O)NC2=CC(N3C=CC=C3)=CC=C2N=1 |
| | Ilaprazole Usage And Synthesis |
| Description | Ilaprazole is a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. A weak base, ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.
| | Uses | Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. | | Definition | ChEBI: Ilaprazole is a sulfoxide and a member of benzimidazoles. |
| | Ilaprazole Preparation Products And Raw materials |
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