生物胞素
| 中文名称 | 生物胞素 |
|---|---|
| 中文同义词 | 生物胞素;(S)-2-氨基-6-(5-(((3AS,4S,6AR)-2-氧代六氢-1H-噻吩并[3,4-D]咪唑-4-基]戊酰胺基)己酸 |
| 英文名称 | Biocytin |
| 英文同义词 | NE-BIOTYNYL-L-LYSINE;N-EPSILON-BIOTIN-L-LYSINE;N-EPSILON-(+)-BIOTINYL-L-LYSINE;N-EPSILON-BIOTINYL-L-LYSINE;N-EPSILON-D-BIOTINYL-L-LYSINE;LYSINE(BIOTINYL)-OH;L-BIOCYTIN;EPSILON-BIOTINOYL-L-LYSINE |
| CAS号 | 576-19-2 |
| 分子式 | C16H28N4O4S |
| 分子量 | 372.48 |
| EINECS号 | |
| 相关类别 | 氨基酸衍生化合物;氨基酸衍生物;天然氨基酸极其衍生物;荧光探针，标记，颗粒和染色;Amino Acids & Derivatives;Biotin Derivatives |
| Mol文件 | 576-19-2.mol |
| 结构式 |  |
生物胞素 性质
| 熔点 | ~245 °C (dec.) (lit.) |
|---|---|
| 比旋光度 | D25 +53° (c = 1.05 in 0.1N NaOH) |
| 沸点 | 748.0±60.0 °C(Predicted) |
| 密度 | 1.234 |
| 储存条件 | -20°C |
| 溶解度 | 碱性溶液（微溶），水（微溶，超声处理） |
| 形态 | 固体 |
| 酸度系数(pKa) | 2.53±0.24(Predicted) |
| 颜色 | 白色至类白色 |
| 旋光性 (optical activity) | [α]20/D +53°, c = 1.05% in 0.1 M NaOH(lit.) |
| 水溶解性 | Soluble in water (50 mM) |
| Merck | 13,1227 |
| BRN | 97197 |
| InChIKey | BAQMYDQNMFBZNA-MNXVOIDGSA-N |
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Human Endogenous Metabolite
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Due to its high affinity for avidin, Biocytin can be visualized by using a host of avidin-conjugated markers at the light and electron microscopic level. Biocytin is used to visualize the morphology of dendritic and axonal arborizations.
The Biocytin wide-field bipolar cell in rabbit retina is a sparsely populated ON cone bipolar cell with a broad dendritic arbor that does not contact all cones in its dendritic field. Identification of bipolar cells by selective uptake of Biocytin, labeled the cones with peanut agglutinin, and then identification of cone types using antibodies against blue cone opsin and red-green cone opsin. The Biocytin-labeled cells selectively contact cones whose outer segments stained for blue cone opsin and avoided cones that do not. Biocytin wide-field bipolar cell is an ON blue cone bipolar cell in the rabbit retina and is homologous to the blue cone bipolar cells that have been previously described in primate, mouse, and ground squirrel retinas.
安全信息
| WGK Germany | 3 |
|---|---|
| 海关编码 | 29362900 |
| 提供商 | 语言 |
|---|---|
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英文
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