Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:AF-DX 384;N-[2-[2-[(DipropylaMino)Methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxaMide CAS:118290-27-0 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| AF-DX 384 Basic information |
Product Name: | AF-DX 384 | Synonyms: | AF-DX 384;N-[2-[2-[(DIPROPYLAMINO)METHYL]-1-PIPERIDINYL]ETHYL]-5,6-DIHYDRO-6-OXO-11H-PYRIDO[2,3-B][1,4]BENZODIAZEPINE-11-CARBOXAMIDE;N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxami;N-(2-(2-((DIPROPYLAMINO)METHYL)PIPERIDIN-1-YL)ETHYL)-6-OXO-5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPINE-11(6H)-CARBOXAMIDE;AF-DX 384 methanesulfonate;11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-, methanesulfonate (1:1) | CAS: | 118290-27-0 | MF: | C27H38N6O2 | MW: | 478.63 | EINECS: | | Product Categories: | Acetylcholine receptor | Mol File: | 118290-27-0.mol | ![AF-DX 384 Structure](CAS/GIF/118290-27-0.gif) |
| AF-DX 384 Chemical Properties |
storage temp. | Store at RT |
| AF-DX 384 Usage And Synthesis |
Uses | AF-DX 384 is a potent mAChR M2/mAChR M4?selective antagonist. | Definition | ChEBI: N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide is a benzodiazepine. | Biological Activity | Potent M 2 /M 4 selective antagonist (pK i values are 8.22, 8.00, 7.51, 7.18 and 6.27 at human M 2 , M 4 , M 1 , M 3 and M 5 receptors respectively). |
| AF-DX 384 Preparation Products And Raw materials |
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