| Company Name: |
Taizhou Crene Biotechnology Co. Ltd.
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| Tel: |
+86-0576-88813233 +86-13396860566 |
| Email: |
sales@pharm-intermediates.com |
| Products Intro: |
Product Name:Iralukast(CGP 45715A)
CAS:151581-24-7
Purity:98% Package:10MG;100MG;500MG;1G
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| Company Name: |
Jinan ponder chemical co. LTD
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| Tel: |
0531-0000 |
| Email: |
thinklifescience@163.com |
| Products Intro: |
Product Name:151581-24-7
CAS:151581-24-7
Purity:99% HPLC Package:1KG;500G;100G;50G;1G
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| | IRALUKAST Basic information |
| Product Name: | IRALUKAST | | Synonyms: | Iralukast [inn];Unii-L1E28E0J8f;7-[(2S,3E,5Z)-10-(4-Acetyl-3-Hydroxy-2-Propylphenoxy)-1-Hydroxy-1-[3-(Trifluoromethyl)Phenyl]Deca-3,5-Dien-2-Yl]Sulfanyl-4-Oxochromene-2-Carboxylic Acid;4H-1-Benzopyran-2-carboxylic acid, 7-[[(1S,2E,4Z)-9-(4-acetyl-3-hydroxy-2-propylphenoxy)-1-[(R)-hydroxy[3-(trifluoromethyl)phenyl]methyl]-2,4-nonadien-1-yl]thio]-4-oxo-;Iralukast (CGP 45715A) | | CAS: | 151581-24-7 | | MF: | C38H37F3O8S | | MW: | 710.76 | | EINECS: | | | Product Categories: | | | Mol File: | 151581-24-7.mol |  |
| | IRALUKAST Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | IRALUKAST Usage And Synthesis |
| Uses | Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1. | | IC 50 | CysLT1: 7.8 (pKi) | | References | [1] Magnus B?ck, et al. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. Br J Pharmacol. 2014 Aug; 171(15): 3551–3574. DOI:10.1111/bph.12665
[2] Valérie Capra, et al. Pharmacological characterization of the cysteinyl-leukotrieneantagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro.Br J Pharmacol. 1998 Feb; 123(3): 590–598. DOI:10.1038/sj.bjp.0701636 |
| | IRALUKAST Preparation Products And Raw materials |
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