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PI 828

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:PI-828
CAS:942289-87-4
Purity:99.39% Package:1mg;46USD|5mg;118USD|10mg;198USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: LEAPCHEM CO., LTD.
Tel: +86-852-30606658
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Products Intro: Product Name:PI 828
CAS:942289-87-4
Purity:0 Package:1g; 5g; 25g; 1kg; 5kg; 25kg Remarks:0
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:PI 828
CAS:942289-87-4
Purity:>=99%(HPLC) Package:$236.9/5mg;$404.9/10mg;$810.9/25mg;$1305.9/50mg;Bulk package Remarks:99%(HPLC)
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel: +8613720134139
Email: orders@jknbiochem.com
Products Intro: Product Name:PI 828
CAS:942289-87-4
Purity:0.98 Package:10G:100G
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:PI 828;2-(4-Morpholinyl)-8-(4-aMinopheny)l-4H-1-benzopyran-4-one
CAS:942289-87-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g

PI 828 manufacturers

  • PI-828
  • PI-828 pictures
  • $46.00 / 1mg
  • 2024-11-01
  • CAS:942289-87-4
  • Min. Order:
  • Purity: 99.39%
  • Supply Ability: 10g
PI 828 Basic information
Product Name:PI 828
Synonyms:PI 828;2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one;8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one;8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one;LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem;LY 294002, 4′-NH2;PI 828,PI828;4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
CAS:942289-87-4
MF:C19H18N2O3
MW:322.36
EINECS:
Product Categories:
Mol File:942289-87-4.mol
PI 828 Structure
PI 828 Chemical Properties
Boiling point 534.2±50.0 °C(Predicted)
density 1.316±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble
pka4.14±0.10(Predicted)
form Off-white solid
color White to yellow
Safety Information
MSDS Information
PI 828 Usage And Synthesis
DefinitionChEBI: 8-(4-aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one is a member of chromones.
General DescriptionA cell-permeable LY 294002 (Cat. Nos. 440202 & 440204) 4′-amino derivative with enhanced potency against p110α/β/δ/γ (IC50 in nM/-fold increase in potency = 183/2.7-, 98/5.7-, 1227/.5-, and 1967/1.9-, respectively). The molecule has been immobilized on epoxy-containing solid surface via the 4′-amine for binding studies and shown to interact with non-PI3K cellular proteins, such as mTOR, ALDH1, Brd4, GSK3β, and CKIIα.
Biological ActivityPI 3-Kinase inhibitor (IC 50 values are 0.098, 0.183, 0.227 and 1.967 μ M for p110 β , p110 α , p110 δ and p110 γ respectively) that displays higher potency than LY 294002 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride). Can be immobilized onto a solid phase.
storageStore at +4°C
PI 828 Preparation Products And Raw materials
Tag:PI 828(942289-87-4) Related Product Information
Phenyl carbamate 2-(Dimethylamino)-8-phenyl-4H-1-benzopyran-4-one LY 294002 HYDROCHLORIDE PI 828 4H-1-Benzopyran-4-one, 2-(diethylamino)- 2-(Diethylamino)-8-phenyl-4H-1-benzopyran-4-one 2-(Etilmetilammino)-8-fenilcromone [Italian]