HEMOPRESSIN (HUMAN, BOVINE, PORCINE)
中文名称 | HEMOPRESSIN (HUMAN, BOVINE, PORCINE) |
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中文同义词 | 选择性CB1受体逆激动剂多肽PVNFKLLSH |
英文名称 | Hemopressin (human, bovine, porcine) |
英文同义词 | Hemopressin (human, bovine, porcine);H-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH;L-Histidine, L-prolyl-L-valyl-L-asparaginyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl- |
CAS号 | 1314035-51-2 |
分子式 | C50H79N13O12 |
分子量 | 1054.24 |
EINECS号 | |
相关类别 | 目录多肽 |
Mol文件 | 1314035-51-2.mol |
结构式 | ![]() |
HEMOPRESSIN (HUMAN, BOVINE, PORCINE) 性质
沸点 | 1491.3±65.0 °C(Predicted) |
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密度 | 1.258±0.06 g/cm3(Predicted) |
储存条件 | Store at -20°C |
酸度系数(pKa) | 2.77±0.10(Predicted) |
形态 | 粉末 |
颜色 | 白色至米白色 |
水溶解性 | Soluble to 1 mg/ml in water |
序列 | H-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH |
Hemopressin causes hypotension in anesthetized rats and is metabolized in vivo and in vitro by endopeptidase 24.15 (EP24.15), neurolysin (EP24.16), and angiotensin-converting enzyme (ACE).
Oral administration of Hemopressin inhibits mechanical hyperalgesia of CCI-rats up to 6h. Hemopressin treatment also decreases Egr-1 immunoreactivity (Egr-1Ir) in the superficial layer of the dorsal horn of the spinal cord of CCI rats.
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%