| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Docetaxel Hydrate
CAS:700367-34-6
Package:1g,500Mg,50Mg,5Mg
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Docetaxel Hydrate
CAS:700367-34-6
|
|
| | Docetaxel Hydrate Basic information |
| Product Name: | Docetaxel Hydrate | | Synonyms: | Paclitaxel Impurity 104;(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca3,4benzo1,2-boxet-12-yl benzoate hydrate | | CAS: | 700367-34-6 | | MF: | C43H53NO14 | | MW: | 807.87922 | | EINECS: | | | Product Categories: | Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents | | Mol File: | 700367-34-6.mol |  |
| | Docetaxel Hydrate Chemical Properties |
| Melting point | 170-174°C | | storage temp. | -20°C Freezer | | solubility | DMF: 5 mg/ml,DMSO: 5 mg/ml,DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml,Ethanol: 1.5 mg/ml | | form | A crystalline solid |
| | Docetaxel Hydrate Usage And Synthesis |
| Description | Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM). It has proven more effective than taxol in preventing the proliferation of cancer cells. Docetaxel has applications in breast cancer and hormone-refractory prostate cancer. This product is intended for research applications. | | Chemical Properties | White Solid | | Uses | A semisynthetic derivative of Paclitaxel(P132500), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. | | Uses | A semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antineoplastic. |
| | Docetaxel Hydrate Preparation Products And Raw materials |
|