Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:PHA-543613 Dihydrochloride CAS:478148-58-2 Package:100Mg,10Mg
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Email: |
marketing@energy-chemical.com |
Products Intro: |
Product Name:PHA-543613 Dihydrochloride CAS:478148-58-2 Purity:NULL Package:100mg;10mg;25mg;50mg;5mg Remarks:NULL
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| PHA-543613 Dihydrochloride Basic information |
| PHA-543613 Dihydrochloride Chemical Properties |
Melting point | >300?C | storage temp. | Refrigerator | solubility | DMSO, Methanol | form | Solid | color | Tan |
| PHA-543613 Dihydrochloride Usage And Synthesis |
Chemical Properties | Tan Solid | Uses | PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer′s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays. |
| PHA-543613 Dihydrochloride Preparation Products And Raw materials |
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