Log in | Join Free | china | japan | germany

11-Piperazinyldibenzo[b,e][1,4]diazepine

Request For Quotation
11-Piperazinyldibenzo[b,e][1,4]diazepine Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:DREADD AGONIST 21
CAS:56296-18-5
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:DREADD agonist 21
CAS:56296-18-5
Purity:98.00% Package:1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:11-Piperazinyldibenzo[b,e][1,4]diazepine
CAS:56296-18-5
Purity:85.0-99.8% Package:1KG;1USD
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:DREADD agonist 21
CAS:56296-18-5
Purity:98% Package:5mg Remarks:V20245
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054
Email: trendseenbio@gmail.com
Products Intro: Product Name:DREADDAgonist21
CAS:56296-18-5
Purity:99% Package:1kg；25kg
11-Piperazinyldibenzo[b,e][1,4]diazepine Basic information
Product Name:11-Piperazinyldibenzo[b,e][1,4]diazepine
Synonyms:11-Piperazinyldibenzo[b,e][1,4]diazepine;DREADD Agonist 21;11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine;DREADD agonist 1;5H-Dibenzo[b,e][1,4]diazepine, 11-(1-piperazinyl)-;Muscarinic acetylcholine receptor,schizophrenia,mAChR,Inhibitor,muscarinic,disease,inhibit,DREADD agonist21,neurodegenerative,acetylcholine,DREADD agonist 21,DREADD,neuronal,hM3Dq,DREADD agonist-21,activation,receptors;11-(Piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
CAS:56296-18-5
MF:C17H18N4
MW:278.35
EINECS:
Product Categories:
Mol File:56296-18-5.mol
11-Piperazinyldibenzo[b,e][1,4]diazepine Structure
11-Piperazinyldibenzo[b,e][1,4]diazepine Chemical Properties
Boiling point 470.1±55.0 °C(Predicted)
density 1.28±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.8(Max Conc. mM)
Ethanol:29.61(Max Conc. mg/mL);106.39(Max Conc. mM)
form A crystalline solid
pka8.56±0.10(Predicted)
color Yellow
Safety Information
MSDS Information
11-Piperazinyldibenzo[b,e][1,4]diazepine Usage And Synthesis
DescriptionDREADD agonist 21 activates hM3Dq (EC50 = 1.7 nM), a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor. It does not agonize the hM3 receptor and displays relatively weaker binding affinities for serotonin 5-HT2A, 5-HT2C, α1A-adrenergic, and histamine H1 receptors (Kis = 66, 170, 280, and 6 nM, respectively).
UsesDREADD agonist 21 is an agonist of hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD). It preferentially binds hM3Dq?DREADDs over endogenous hM3?receptors.
storageRoom temperature
11-Piperazinyldibenzo[b,e][1,4]diazepine Preparation Products And Raw materials
Tag:11-Piperazinyldibenzo[b,e][1,4]diazepine(56296-18-5) Related Product Information