Company Name: |
ChemPep, Inc.
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Tel: |
+1 (888) 615-9178 / (561) 791-8787 |
Email: |
service@chempep.com |
Products Intro: |
Product Name:mPEG16-Propyne CAS:2169967-47-7 Purity:95% Package:1 g, 5 g Remarks:PEGylation Reagents
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Company Name: |
Amatek Scientific Co. Ltd.
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Tel: |
0512-56316828 |
Email: |
info@amateksci.com |
Products Intro: |
Product Name:mPEG16-Propyne CAS:2169967-47-7 Purity:97% HPLC Package:1g;5g;25g;100g
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Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
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Tel: |
010-60605840 15801484223; |
Email: |
psaitong@jm-bio.com |
Products Intro: |
Product Name:Propargyl-PEG17-methane CAS:2169967-47-7 Purity:95% Package:100mg;250mg;1g
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:Propargyl-PEG17-methane;Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane CAS:2169967-47-7 Purity:99.69% Package:100 mg;200 mg;500 mg
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| MPEG16-Propyne Basic information |
Product Name: | MPEG16-Propyne | Synonyms: | MPEG16-Propyne;2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne;Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane;mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne | CAS: | 2169967-47-7 | MF: | C36H70O17 | MW: | 774.93 | EINECS: | | Product Categories: | | Mol File: | 2169967-47-7.mol | |
| MPEG16-Propyne Chemical Properties |
| MPEG16-Propyne Usage And Synthesis |
Biological Activity | Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| MPEG16-Propyne Preparation Products And Raw materials |
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