| Company Name: |
S.Z. PhyStandard Bio-Tech. Co., Ltd.
|
| Tel: |
0755-4000505016 13380397412 |
| Email: |
3001272453@qq.com |
| Products Intro: |
Product Name:Aprepitant intermediate 1
CAS:1185503-48-3
Purity:99% HPLC Package:10mg;25mg;50mg;100mg
|
| Company Name: |
Shanghai Ranxon Chemical Co., Ltd.
|
| Tel: |
13148101715 |
| Email: |
2073632910@qq.com |
| Products Intro: |
Product Name:(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine hydrochloride
CAS:1185503-48-3
Purity:>95% Package:5Mg, 10Mg, 50Mg, 100Mg, 1g, 2g
|
| Company Name: |
Nanjing XiZe Biotechnology CO., Ltd.
|
| Tel: |
025-58362220 15250997978 |
| Email: |
1511893459@qq.com |
| Products Intro: |
Product Name:Aprepitant Impurity 12 HCl
CAS:1185503-48-3
Purity:95% HPLC Package:10mg;25mg;50mg;100mg;250mg;500mg;1g
|
|
| | (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Basic information |
| Product Name: | (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride | | Synonyms: | (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride;Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-Aprepitant;Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)-;Aprepitant intermediate 1 HCl;Aprepitant intermediate 1;Arepitam intermediate 1 hydrochloride;Fosaprepitant Impurity 31;Aprepitant Impurity 12 HCl | | CAS: | 1185503-48-3 | | MF: | C20H18F7NO2 | | MW: | 437.35 | | EINECS: | | | Product Categories: | | | Mol File: | 1185503-48-3.mol | ![(2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Structure](CAS/20150408/GIF/1185503-48-3.gif) |
| | (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Chemical Properties |
| Boiling point | 387.9±42.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | pka | 6.93±0.60(Predicted) |
| | (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Usage And Synthesis |
| Uses | Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. |
| | (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Preparation Products And Raw materials |
|