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BOC Sciences
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Product Name:Aprepitant Impurity 1
CAS:327623-37-0
Purity:> 95% Remarks:https://www.bocsci.com/product/aprepitant-impurity-1-cas-327623-37-0-466710.html
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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| Products Intro: |
Product Name:Aprepitant Impurity 1 HCl
CAS:327623-37-0
Purity:98% HPLC Package:10mg;25mg;50mg
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| | (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Basic information |
| Product Name: | (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine | | Synonyms: | (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine;(2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride;(2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-Methylphenyl)ethoxy]-3-(4-fluorophenyl)Morpholine;Aprepitant Impurity 1;Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant;Aprepitant Impurity 11;Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer;Fosaprepitant Impurity 30 | | CAS: | 327623-37-0 | | MF: | C20H18F7NO2 | | MW: | 437.35 | | EINECS: | | | Product Categories: | | | Mol File: | 327623-37-0.mol |  |
| | (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Chemical Properties |
| Boiling point | 387.9±42.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | pka | 6.93±0.60(Predicted) |
| | (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Usage And Synthesis |
| Uses | Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. |
| | (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Preparation Products And Raw materials |
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