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| | Ethyl (triphenylphosphoranylidene)acetate Basic information | | Description |
| | Ethyl (triphenylphosphoranylidene)acetate Chemical Properties |
| | Ethyl (triphenylphosphoranylidene)acetate Usage And Synthesis |
| Description | Ethyl (triphenylphosphoranylidene)acetate is a common Wittig reagent in organic synthesis as well as a cholinesterase inhibitor that inhibits both AChE and BChE. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone.
| | Chemical Properties | Off-White Solid | | Uses | A common Wittig reagent. A cholinesterase inhibitor. | | Uses | (Ethoxycarbonylmethylene)triphenylphosphoran is used as a Wittig reagent in organic synthesis. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone. It acts as an inhibitor and inhibits the activity of cholinesterase. | | reaction suitability | reaction type: C-C Bond Formation | | Purification Methods | Crystallise it by dissolving it in AcOH and adding pet ether (b 40-50o) to give colourless plates. UV (A 1% ): 222nm (865) and 268nm (116) [Isler et max 1mm al. Helv Chim Acta 40 1242 1957]. [Beilstein 16 IV 977.] |
| | Ethyl (triphenylphosphoranylidene)acetate Preparation Products And Raw materials |
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