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| | 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside Basic information |
| Product Name: | 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside | | Synonyms: | 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside;2-Amino-6-chloropurine-9-(2’-O-propargyl)riboside;2-Amino-6-chloro-9-(2'-O-propargyl-b-D-ribofuranosyl)purine;2-Amino -6-chloropurine-9-(2’-O-pro pargyl) riboside;2-Amino-6-chloro-2'-O-propargylpurine-9-riboside | | CAS: | 2095417-35-7 | | MF: | C13H14ClN5O4 | | MW: | 339.73 | | EINECS: | | | Product Categories: | | | Mol File: | 2095417-35-7.mol |  |
| | 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside Chemical Properties |
| InChI | InChI=1/C13H14ClN5O5/c1-2-3-22-9-8(21)6(20)4-23-12(9)24-19-5-16-7-10(14)17-13(15)18-11(7)19/h1,5-6,8-9,12,20-21H,3-4H2,(H2,15,17,18)/t6-,8-,9-,12?/s3 | | InChIKey | QYKKSMWYIBCIBN-SFKBCKQCNA-N | | SMILES | N1C2=C(N=C(N)N=C2Cl)N(OC2OC[C@@H](O)[C@@H](O)[C@H]2OCC#C)C=1 |&1:14,16,18,r| |
| | 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside Usage And Synthesis |
| Description |
2-Amino-6-chloro-2'-O-propargylpurine-9-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. It is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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| | 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside Preparation Products And Raw materials |
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