CS-2092
中文名称 | CS-2092 |
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中文同义词 | 化合物RSV604 |
英文名称 | RSV604 |
英文同义词 | RSV604;CS-2092;Urea, N-[(3S)-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(2-fluorophenyl)-;(S)-1-(2-fluoro-phenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea;RSV604;RSV 604;virus,Respiratory syncytial virus,A 60444,respiratory,protein,inhibit,RSV,syncytial,A-60444,Inhibitor,A60444,RSV604,RSV 604,nucleocapsid,RSV-604 |
CAS号 | 676128-63-5 |
分子式 | C22H17FN4O2 |
分子量 | 388.39 |
EINECS号 | |
相关类别 | |
Mol文件 | 676128-63-5.mol |
结构式 | ![]() |
CS-2092 性质
储存条件 | Store at -20°C |
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溶解度 | DMF:30mg/mL; DMF:PBS (pH 7.2) (1:20):0.04 mg/ml; DMSO:20mg/mL;乙醇:5mg/mL |
形态 | 固体 |
颜色 | 白色至米白色 |
Target | Value |
RSV
(Cell-free assay) | 0.86 μM(EC50) |
RSV604 (5 days) inhibits the growth of four laboratory strains of RSV (RSS, Long, A2 and B), with EC
50
s ranging from 0.5 to 0.9 μM in plaque reduction assay.
RSV604 (6 days) inhibits RSV-induced HEp-2 cell death, with an EC
50
of 0.86 μM.
RSV604 (3 days) reduces viral antigen synthesis in RSV-infected HEp-2 cells, with an EC
50
of 1.7 μM.
RSV604 (1-20 μM; 7 days) dose-dependently inhibits RSV infection in human airway epithelial (HAE) cells, with no gross cytotoxicity, leakage of basolateral fluid to the apical surface, or alteration of cilium beat frequency.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/08/19 | HY-12993 | CS-2092 RSV604 | 676128-63-5 | 5mg | 600元 |
2024/08/19 | HY-12993 | CS-2092 RSV604 | 676128-63-5 | 10mM * 1mLin DMSO | 660元 |