奥贝胆酸杂质9
| 中文名称 | 奥贝胆酸杂质9 |
|---|---|
| 中文同义词 | 牛磺-胆固醇;牛磺酰奥贝胆酸;牛磺-奥贝胆酸;2H4]-牛磺酸-奥贝胆酸;牛磺酸奥贝胆酸 |
| 英文名称 | Tauro Obeticholic acid |
| 英文同义词 | Obeticholic Acid Impurity 4/Tauro-Obeticholic Acid/2-((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-Ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid;Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]-;Obeticholic Acid Impurity 56;Tauro-Obeticholic Acid DISCONTINUED. Please see T009025.;2H4]-Tauro-obeticholic acid;microorganisms,FXR,Tauro-Obeticholic acid,colon,NR1H4,TauroObeticholic acid,inhibit,ileum,Inhibitor,Tauro Obeticholic acid,metabolite，liver;Tauro-Obeticholic Acid |
| CAS号 | 863239-61-6 |
| 分子式 | C28H49NO6S |
| 分子量 | 527.76 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 863239-61-6.mol |
| 结构式 |  |
奥贝胆酸杂质9 性质
| 密度 | 1.177±0.06 g/cm3(Predicted) |
|---|---|
| 储存条件 | Store at -20°C, protect from light, stored under nitrogen |
| 溶解度 | DMSO：可溶；甲醇：可溶；水溶性 |
| 形态 | 固体 |
| 酸度系数(pKa) | 1.42±0.50(Predicted) |
| 颜色 | 白色至黄色 |
| 稳定性 | 吸湿性 |
Tauro-Obeticholic acid 是牛磺酸的活性代谢物。Obeticholic Acid 是一种口服生物可利用的法尼样X受体 (FXR) 激动剂。
Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/08/19 | HY-135399 | 奥贝胆酸杂质9 Tauro-Obeticholic acid | 863239-61-6 | 1mg | 5500元 |