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ChemStrong Scientific Co.,Ltd
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Product Name:Fosaprepitant Impurity U
CAS:219821-37-1
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Shanghai Kewel Chemical Co., Ltd.
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| Tel: |
021-64609169 18901607656 |
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greensnown@163.com |
| Products Intro: |
Product Name:Fosaprepitant Impurity U
CAS:219821-37-1
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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| | Aprepitant Impurity 9 Basic information |
| Product Name: | Aprepitant Impurity 9 | | Synonyms: | Aprepitant Impurity 9;Aprepitant Open-Ring Methyl Ester Impurity;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant Impurity 47;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate | | CAS: | 219821-37-1 | | MF: | C24H25F7N4O4 | | MW: | 566.47 | | EINECS: | | | Product Categories: | | | Mol File: | 219821-37-1.mol |  |
| | Aprepitant Impurity 9 Chemical Properties |
| density | 1.43±0.1 g/cm3(Predicted) | | solubility | soluble in Chloroform, Dichloromethane, Methanol | | form | Solid | | pka | 7.86±0.43(Predicted) | | color | Pale-Yellow |
| | Aprepitant Impurity 9 Usage And Synthesis |
| Uses | N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. |
| | Aprepitant Impurity 9 Preparation Products And Raw materials |
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