- Dihydrocyclosporin A
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- $129.00 / 1mg
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2024-11-19
- CAS:59865-15-5
- Min. Order:
- Purity: 99.50%
- Supply Ability: 10g
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| | DIHYDROCYCLOSPORIN A Basic information |
| Product Name: | DIHYDROCYCLOSPORIN A | | Synonyms: | DIHYDROCYCLOSPORIN A;Dihydrocyclosporin;(3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-];(3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A;Cyclosporin A Dihydro IMpurity;Dihydrocyclosporine A;Cyclosporin Impurity 10 | | CAS: | 59865-15-5 | | MF: | C62H113N11O12 | | MW: | 1204.63 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Peptides;Pharmaceuticals | | Mol File: | 59865-15-5.mol |  |
| | DIHYDROCYCLOSPORIN A Chemical Properties |
| Melting point | 120-125?C | | Boiling point | 1285.3±65.0 °C(Predicted) | | density | 1.012±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | form | Solid | | pka | 13.33±0.70(Predicted) | | color | White | | InChIKey | TYFOVYYNQGNDKH-AAJDKDKZNA-N |
| | DIHYDROCYCLOSPORIN A Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Dihydrocyclosporin A (DHCsA-d) is cyclosporine A (CsA) derivative. DHCsA-d significantly inhibited promastigotes and intracellular amastigotes, but it is highly cytotoxic. | | Uses | Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections. | | Uses | A Cyclosporin A (C988900) analog, an immunosuppressant. | | Side effects | Dihydrocyclosporine A has no obvious nephrotoxic effect, but it exhibits hepatotoxic effects, often leading to hypertension. |
| | DIHYDROCYCLOSPORIN A Preparation Products And Raw materials |
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